{"id":"W4398177693","doi":"10.1002/2211-5463.13814","title":"<scp>CSF</scp> amino acid profiles in <scp>ICV</scp>‐streptozotocin‐induced sporadic Alzheimer's disease in male Wistar rat: a metabolomics and systems biology perspective","year":2024,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Tehran University of Medical Sciences and Health Services","keywords":"Streptozotocin; Disease; Metabolomics; Perspective (graphical); Biology; Amino acid; Alzheimer's disease; Biochemistry; Pharmacology; Medicine; Endocrinology; Bioinformatics; Internal medicine; Diabetes mellitus; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001016037,0.000488585,0.0003698159,0.0007616023,0.0001679361,0.0002861613,0.000130929,0.0003623244,0.0005813991],"category_scores_gemma":[0.0000945686,0.0001279324,0.0002449604,0.0003400184,0.0003287431,0.0002290487,0.0001234986,0.0006853549,0.0001696054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002692242,"about_ca_system_score_gemma":0.0002720872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002272079,"about_ca_topic_score_gemma":0.002310431,"domain_scores_codex":[0.9999136,0.000005866278,0.00000933205,0.00002089673,0.00002602943,0.0000243585],"domain_scores_gemma":[0.9998432,0.0000112116,0.00005650891,0.00001002889,0.0000304607,0.0000485259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008212012,0.00006468855,0.001141468,0.00002902414,0.00001551633,0.0001460529,0.00002941231,0.00002842337,0.9961843,0.00002124294,0.00004934066,0.001469268],"study_design_scores_gemma":[0.00004248647,0.00228008,0.1042401,0.00001417488,0.0000910454,0.0009020298,0.0001485869,0.0005869278,0.8898913,0.00007492048,0.001708223,0.00002001771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966494,0.0009960398,0.0005082812,0.0000767829,0.00002557118,0.00001871113,0.00114804,0.0000559998,0.0005210587],"genre_scores_gemma":[0.9935611,0.001266033,0.001273989,0.000100124,0.00002197598,0.00005852463,0.001684496,0.00002976226,0.002003934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002272079,"threshold_uncertainty_score":0.004517674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04216077736073297,"score_gpt":0.3021810823977557,"score_spread":0.2600203050370227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}