{"id":"W4398182545","doi":"10.1093/lambio/ovae048","title":"Comprehensive comparative analysis of the periodontal pathogen <i>Porphyromonas gingivalis</i>: exploring the pan-genome, the reconstruction of the gene regulatory network and genome-scale metabolic network","year":2024,"lang":"en","type":"article","venue":"Letters in Applied Microbiology","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Sistema Nacional de Investigadores; Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México; Comisión de Operación y Fomento de Actividades Académicas, Instituto Politécnico Nacional; Universidad Nacional Autónoma de México","keywords":"Porphyromonas gingivalis; Biology; Virulence; Microbiology; Bacterial adhesin; Fimbria; Genetics; Gene; Comparative genomics; Genome; Secretion; Genomics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001383568,0.0003697845,0.0003822799,0.0008658242,0.0003377243,0.0004520368,0.0001922726,0.0003076788,0.001077007],"category_scores_gemma":[0.0001957008,0.0001285192,0.0005060057,0.001413662,0.0001535488,0.0002763133,0.000379661,0.0003574518,0.0004030264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002298437,"about_ca_system_score_gemma":0.000405801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001458939,"about_ca_topic_score_gemma":0.002015986,"domain_scores_codex":[0.9998719,0.00001182654,0.000007064224,0.00004585445,0.00003339633,0.00003006675],"domain_scores_gemma":[0.9998841,0.0000203732,0.00003197513,0.00001256179,0.00002099567,0.00002995924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000322682,0.00003162056,0.004162714,0.0003208188,0.00004786822,0.0002929773,0.0001125676,0.0004089728,0.9833413,0.0001691262,0.0002444726,0.01054491],"study_design_scores_gemma":[0.00003895242,0.001015975,0.6766139,0.0001401198,0.0007143614,0.004444876,0.001016515,0.008651894,0.2531084,0.001170544,0.05300127,0.00008308566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763309,0.00494778,0.006119792,0.0001445438,0.00001794182,0.00004089253,0.01008127,0.0001548803,0.00216197],"genre_scores_gemma":[0.9453721,0.004106957,0.0177098,0.000131752,0.00002691957,0.00006870208,0.03067889,0.0001238952,0.001781105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001458939,"threshold_uncertainty_score":0.003602922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02408228089181846,"score_gpt":0.2451125667501786,"score_spread":0.2210302858583602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}