{"id":"W4398193875","doi":"10.1016/j.jcyt.2024.03.060","title":"ACCUTOX®-REPROGRAMMED MESENCHYMAL STROMAL CELLS: A LIVING BIOTHERAPEUTIC FOR CANCER IMMUNOTHERAPY","year":2024,"lang":"en","type":"article","venue":"Cytotherapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Mesenchymal stem cell; Stromal cell; Cancer research; Immunotherapy; Cancer immunotherapy; Chemistry; Cancer; Medicine; Biology; Cell biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001963581,0.0002602374,0.0001973377,0.00008064416,0.00008037739,0.0001691464,0.0002900941,0.000194543,0.0001862581],"category_scores_gemma":[0.00000747047,0.0002279674,0.000282415,0.0001283111,0.00007983275,0.00001056935,0.00002793694,0.0001006641,0.00001782248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003241362,"about_ca_system_score_gemma":0.0001634334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006055019,"about_ca_topic_score_gemma":0.00005832994,"domain_scores_codex":[0.9986016,0.00004444892,0.0002357792,0.0005737742,0.0001175801,0.0004268344],"domain_scores_gemma":[0.9993842,0.00004576483,0.00004782012,0.0003812275,0.0000729864,0.00006800063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001756026,0.00005845458,0.0002951763,0.00003462359,0.0003662738,0.000002573436,0.0002691154,0.00001795897,0.8845999,0.00005920293,0.002137844,0.1119833],"study_design_scores_gemma":[0.0004875516,0.0009174686,0.0003136661,0.0001054448,0.00002400296,0.00001008577,0.000114891,0.0007759363,0.5883686,0.00009557505,0.4084197,0.0003671176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.93817,0.03953017,0.0195634,0.0004917205,0.001178297,0.0006501854,0.0000812566,0.0001921403,0.0001427997],"genre_scores_gemma":[0.9855118,0.006904242,0.001242776,0.001353983,0.001125906,0.000459762,0.00003330121,0.0001563808,0.003211845],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4062818,"threshold_uncertainty_score":0.929624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02013952017395751,"score_gpt":0.3181044530110561,"score_spread":0.2979649328370986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}