{"id":"W4398194000","doi":"10.1016/j.jcyt.2024.04.051","title":"ENGINEERING CAR-EXPRESSING INNATE LYMPHOID CELLS (ILCS) FROM HUMAN PLURIPOTENT STEM CELLS (HPSCS) FOR CANCER IMMUNOTHERAPY","year":2024,"lang":"en","type":"article","venue":"Cytotherapy","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Induced pluripotent stem cell; Innate lymphoid cell; Cancer immunotherapy; Biology; Immunotherapy; Cancer research; Immunology; Innate immune system; Immune system; Embryonic stem cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002873745,0.0002095476,0.0001769887,0.0002888699,0.0001250695,0.0004392339,0.0001597382,0.0003780448,0.00208474],"category_scores_gemma":[0.0001792656,0.00009553409,0.000241216,0.0001923287,0.0002022144,0.0001792645,0.0002354032,0.000730691,0.0006642744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001529268,"about_ca_system_score_gemma":0.0002194059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002532713,"about_ca_topic_score_gemma":0.0004990078,"domain_scores_codex":[0.9998465,0.00002449649,0.00001439668,0.00002741628,0.00005625535,0.00003087005],"domain_scores_gemma":[0.9999137,0.00002374065,0.00001676722,0.00001096465,0.00002047228,0.00001427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006482322,0.00003480624,0.0003469891,0.0001060941,0.00000733451,0.00009289892,0.00006442879,0.0002509848,0.988987,0.00107131,0.0002204705,0.008752827],"study_design_scores_gemma":[0.00003078896,0.0002157558,0.0007983179,0.00001652295,0.00003404552,0.0002485054,0.00005911157,0.001762153,0.982884,0.0002337745,0.01371226,0.00000471219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8569943,0.00592057,0.1231152,0.000543663,0.0003008458,0.0006004896,0.001202294,0.0006927113,0.01062989],"genre_scores_gemma":[0.9755903,0.001534645,0.01730285,0.0002298258,0.00003100707,0.0001663905,0.0005167018,0.00004674535,0.004581513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00208474,"threshold_uncertainty_score":0.006974101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02884696111198442,"score_gpt":0.3121160642707506,"score_spread":0.2832691031587662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}