{"id":"W4398194079","doi":"10.1016/j.jcyt.2024.03.076","title":"ALLOGENEIC UMBILICAL-CORD DERIVED MESENCHYMAL STROMAL CELLS MSC(UC) AS TREATMENT FOR SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): SAFETY AND EARLY CLINICAL/BIOLOGICAL RESULTS FROM A PHASE I-II PROOF-OF-CONCEPT CLINICAL STUDY","year":2024,"lang":"en","type":"article","venue":"Cytotherapy","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Clinical endpoint; Mesenchymal stem cell; Umbilical cord; Adverse effect; Prednisone; Internal medicine; Clinical trial; Gastroenterology; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006785758,0.0003326008,0.0005445965,0.0002147609,0.0001613783,0.0005291319,0.0002205988,0.0004535714,0.001546143],"category_scores_gemma":[0.0002944309,0.00008272254,0.0004182882,0.0002179331,0.0003367436,0.000190904,0.0001614744,0.000967667,0.0002758011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000189352,"about_ca_system_score_gemma":0.0004218625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002509173,"about_ca_topic_score_gemma":0.0006343549,"domain_scores_codex":[0.9998044,0.00007618988,0.0000119879,0.00002493551,0.00005027168,0.00003217747],"domain_scores_gemma":[0.9998384,0.00004420634,0.00003591986,0.00001680452,0.0000198625,0.00004484792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.06540284,0.02651159,0.003709493,0.002214932,0.0006121005,0.0003672073,0.0002321264,0.00225377,0.5704293,0.0007707715,0.002984228,0.3245117],"study_design_scores_gemma":[0.03701767,0.5558665,0.01537331,0.0002800146,0.001370375,0.001075845,0.0002330636,0.003126768,0.3617381,0.0005104418,0.02336772,0.00004030469],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809896,0.012429,0.002805444,0.0003270835,0.0002196261,0.0006661147,0.0004084199,0.00007795907,0.00207675],"genre_scores_gemma":[0.9895614,0.005740593,0.001741082,0.0003553535,0.0001064391,0.0003198757,0.0005772492,0.00001116282,0.001586898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001546143,"threshold_uncertainty_score":0.005172372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1340224372777825,"score_gpt":0.4378657125006425,"score_spread":0.30384327522286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}