{"id":"W4398194079","doi":"10.1016/j.jcyt.2024.03.076","title":"ALLOGENEIC UMBILICAL-CORD DERIVED MESENCHYMAL STROMAL CELLS MSC(UC) AS TREATMENT FOR SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): SAFETY AND EARLY CLINICAL/BIOLOGICAL RESULTS FROM A PHASE I-II PROOF-OF-CONCEPT CLINICAL STUDY","year":2024,"lang":"en","type":"article","venue":"Cytotherapy","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Clinical endpoint; Mesenchymal stem cell; Umbilical cord; Adverse effect; Prednisone; Internal medicine; Clinical trial; Gastroenterology; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002808756,0.0006305699,0.002208465,0.0001690337,0.0002114534,0.00009215748,0.0003785999,0.0006365677,0.000251673],"category_scores_gemma":[0.0006896122,0.0004202207,0.0007739252,0.000362102,0.0006994798,0.00009200661,0.0001497019,0.000609992,0.0000328822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002175668,"about_ca_system_score_gemma":0.0006698146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002543449,"about_ca_topic_score_gemma":0.00003246536,"domain_scores_codex":[0.9924336,0.001137378,0.002949373,0.001940001,0.0006997043,0.0008399587],"domain_scores_gemma":[0.9927078,0.0047056,0.0003920795,0.001138886,0.0002755845,0.0007800884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2325149,0.03380366,0.1009735,0.0005958955,0.008186949,0.00371706,0.01012667,0.00001557351,0.1231922,0.0002371171,0.002326362,0.4843101],"study_design_scores_gemma":[0.2457088,0.5729113,0.02036586,0.002490402,0.002018043,0.002166734,0.004448948,0.00436046,0.09367237,0.0007195359,0.04885244,0.002285073],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831218,0.005529846,0.0007769517,0.0005721314,0.0009395572,0.008227864,0.0004849093,0.0001945654,0.0001524075],"genre_scores_gemma":[0.992605,0.001354091,0.001740085,0.0001086455,0.0008332777,0.0004041549,0.0001276992,0.0001123349,0.00271475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5391077,"threshold_uncertainty_score":0.9998249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1340224372777825,"score_gpt":0.4378657125006425,"score_spread":0.30384327522286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}