{"id":"W4398205203","doi":"10.7554/elife.89377.4","title":"Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia","year":2024,"lang":"en","type":"article","venue":"eLife","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"China Scholarship Council; Deutsche Forschungsgemeinschaft; European Society of Cardiology; Deutsche Stiftung für Herzforschung; Deutsches Zentrum für Herz-Kreislaufforschung","keywords":"Macrophage polarization; Macrophage; Proinflammatory cytokine; Homeostasis; Biology; Monocyte; Inflammation; Immune system; Immunology; Crosstalk; Ventricular remodeling; Myocardial infarction; Cell biology; Phenotype; Cardiac function curve; M2 Macrophage; Context (archaeology); Medicine; Internal medicine; In vitro; Gene; Genetics; Heart failure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003275449,0.0001952496,0.0004944058,0.0001316449,0.00006701454,0.0001539268,0.00003762842,0.0001248955,0.00005327796],"category_scores_gemma":[0.00008303738,0.0001557139,0.0002948737,0.0001784363,0.00003066133,0.00005466749,0.0001152946,0.0002433315,0.00007363606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007908249,"about_ca_system_score_gemma":0.00008884905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008140341,"about_ca_topic_score_gemma":0.000003667469,"domain_scores_codex":[0.9984947,0.00004547248,0.0002954786,0.0004283336,0.0004044271,0.0003315873],"domain_scores_gemma":[0.9992259,0.00007244091,0.00001943965,0.000253995,0.000103753,0.0003244346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001574451,0.00004699404,0.0278034,0.001019892,0.001486239,0.000407031,0.002965736,0.0000912575,0.8476746,0.0002181439,0.09359551,0.02311673],"study_design_scores_gemma":[0.002770858,0.0005450965,0.4545715,0.004412449,0.00194194,0.0001579391,0.000404308,0.002672442,0.166702,0.00006106102,0.3645436,0.00121678],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9703626,0.02381762,0.0007156782,0.002370713,0.001411138,0.0005001566,0.00009466879,0.0001682597,0.0005591429],"genre_scores_gemma":[0.9940541,0.001219982,0.0006495454,0.0009047951,0.001776722,0.00005013124,0.00003615457,0.00004830234,0.001260284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6809726,"threshold_uncertainty_score":0.6349827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01229201782121022,"score_gpt":0.2822528726141212,"score_spread":0.269960854792911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}