{"id":"W4398216523","doi":"10.17504/protocols.io.36wgq72n3vk5/v4","title":"HTTM : Transposon mutagenesis v2","year":2023,"lang":"en","type":"preprint","venue":"","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Transposon mutagenesis; Transposable element; Mutagenesis; Insertional mutagenesis; Sleeping Beauty transposon system; Genetics; DNA Transposable Elements; Computational biology; Biology; Computer science; Mutation; Mutant; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001858035,0.003023501,0.002471811,0.003390312,0.001493636,0.001724216,0.003369038,0.001871128,0.1410256],"category_scores_gemma":[0.001743489,0.00260231,0.001785672,0.001894094,0.0009758352,0.001111286,0.002528272,0.005405241,0.1655494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008442876,"about_ca_system_score_gemma":0.001307727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001848102,"about_ca_topic_score_gemma":0.00403733,"domain_scores_codex":[0.9979183,0.0003655915,0.0002244295,0.000568746,0.0006405997,0.0002823308],"domain_scores_gemma":[0.9992161,0.0001874522,0.00004630621,0.0003605387,0.00007333014,0.0001161972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006979707,0.0002772133,0.0004109557,0.002358906,0.0001420633,0.0004557413,0.0003231204,0.0006359485,0.6334412,0.009112188,0.2779544,0.07419033],"study_design_scores_gemma":[0.0002630284,0.0002281614,0.00166843,0.0002537333,0.0001216375,0.00142719,0.00006986462,0.001776515,0.3655855,0.003509746,0.6249035,0.0001926965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.01127948,0.00365074,0.5789019,0.001090525,0.002126188,0.00534524,0.2364509,0.1117071,0.04944789],"genre_scores_gemma":[0.04408055,0.004947117,0.348803,0.001405048,0.0002917922,0.008378006,0.3914149,0.06404006,0.1366395],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.1410256,"threshold_uncertainty_score":0.4717776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02291315027108954,"score_gpt":0.2623573369022548,"score_spread":0.2394441866311652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}