{"id":"W4398219764","doi":"10.1101/2024.05.20.594961","title":"Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Immunology; Biology; Interferon; Immune system; Innate immune system; Virology; Virus; Interferon type I; Plasmacytoid dendritic cell; Dendritic cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002318723,0.0003995607,0.0003080425,0.0004013117,0.0001659199,0.0004453231,0.0002072893,0.0005048304,0.001436348],"category_scores_gemma":[0.000174855,0.000215403,0.0002542662,0.0001310166,0.0004507721,0.0002208031,0.0003158311,0.001143814,0.000523956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002916374,"about_ca_system_score_gemma":0.0001861919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002002066,"about_ca_topic_score_gemma":0.0002721175,"domain_scores_codex":[0.9995491,0.00007274849,0.00004413664,0.0001264581,0.00009492825,0.0001126158],"domain_scores_gemma":[0.9995498,0.00006873099,0.0001408199,0.00008162101,0.00003034769,0.0001285465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002112009,0.00002649812,0.0002351681,0.00002431052,0.000002755367,0.0000451372,0.00001051765,0.0000399241,0.9986699,0.0001266713,0.00003843497,0.0005694966],"study_design_scores_gemma":[0.00003666803,0.0003433934,0.004854038,0.00001304293,0.00001937931,0.0003555016,0.00003801413,0.0005769343,0.9907794,0.0001194302,0.002857755,0.000006533096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928416,0.001187775,0.002737497,0.0001258816,0.00005367134,0.00003101194,0.001312889,0.0001170155,0.001592728],"genre_scores_gemma":[0.9928396,0.0004561072,0.00196387,0.0000969023,0.00001808429,0.00005759182,0.0009587763,0.0000788028,0.0035302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001436348,"threshold_uncertainty_score":0.004805088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01623927210207511,"score_gpt":0.2396042854001714,"score_spread":0.2233650132980963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}