{"id":"W4398235118","doi":"10.1080/19490976.2024.2351478","title":"Pathogenesis and therapeutic opportunities of gut microbiome dysbiosis in critical illness","year":2024,"lang":"en","type":"review","venue":"Gut Microbes","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; University of Calgary","keywords":"Dysbiosis; Microbiome; Critical illness; Gut flora; Intensive care medicine; Biology; Intensive care unit; Adverse effect; Disease; Bioinformatics; Medicine; Immunology; Critically ill; Internal medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005584582,0.0006459327,0.001015694,0.001715937,0.0002572099,0.0008944827,0.0007378767,0.001297831,0.003321834],"category_scores_gemma":[0.0008804481,0.0001818965,0.0004772905,0.001217041,0.0004422539,0.001007324,0.0008043082,0.00196739,0.00133839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005144464,"about_ca_system_score_gemma":0.0009233658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005354058,"about_ca_topic_score_gemma":0.001128279,"domain_scores_codex":[0.999838,0.00004185218,0.00002066074,0.00002507985,0.00005609897,0.00001831285],"domain_scores_gemma":[0.9997074,0.0001536767,0.00003160052,0.0000083996,0.00006640929,0.0000324934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001260715,0.00008322555,0.0001708433,0.0180769,0.0001015976,0.0002262357,0.00007606539,0.0004270057,0.002155949,0.00630853,0.03055245,0.941695],"study_design_scores_gemma":[0.00002947483,0.0001659186,0.0009953778,0.006362231,0.0001199548,0.001291879,0.00008256321,0.0001297412,0.0004939562,0.003919987,0.986388,0.00002081867],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009191041,0.9985464,0.00009099691,0.0003770954,0.0002641438,0.000002963174,0.00001070352,0.000005011201,0.0006108623],"genre_scores_gemma":[0.0005854212,0.9984097,0.0001352888,0.000253665,0.0002361441,0.000005521173,0.00001791952,0.000001162664,0.0003551577],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003321834,"threshold_uncertainty_score":0.01111263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08546710615380751,"score_gpt":0.3794512939914076,"score_spread":0.2939841878376001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}