{"id":"W4398235118","doi":"10.1080/19490976.2024.2351478","title":"Pathogenesis and therapeutic opportunities of gut microbiome dysbiosis in critical illness","year":2024,"lang":"en","type":"review","venue":"Gut Microbes","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; University of Calgary","keywords":"Dysbiosis; Microbiome; Critical illness; Gut flora; Intensive care medicine; Biology; Intensive care unit; Adverse effect; Disease; Bioinformatics; Medicine; Immunology; Critically ill; Internal medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002942732,0.0005383143,0.001274997,0.0003582663,0.0000659874,0.00005104821,0.0003106038,0.0006795853,0.00003412277],"category_scores_gemma":[0.00002992784,0.0004493692,0.0003662914,0.0002163976,0.000459052,0.000003333801,0.0003161599,0.0002492965,0.00002225301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003961763,"about_ca_system_score_gemma":0.0004565025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003937824,"about_ca_topic_score_gemma":0.0000417643,"domain_scores_codex":[0.9977703,0.0002058327,0.0007806041,0.0007065531,0.00007226534,0.000464411],"domain_scores_gemma":[0.9991565,0.00004713286,0.0001473778,0.0004666925,0.00007495005,0.0001073705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001811898,0.0001631365,0.00001774183,0.05672512,0.0003029277,0.00005308466,0.0001950088,4.497307e-8,0.4627277,0.0004367033,0.00241999,0.4769404],"study_design_scores_gemma":[0.0001447995,0.0001156847,0.00002595163,0.005638718,0.0006773902,0.0002746314,0.0001456971,2.235501e-7,0.001425927,0.00004188079,0.9909558,0.0005532907],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004116549,0.9940762,0.00001040154,0.0001129707,0.0003193679,0.0004155341,0.0008431295,0.00001486739,0.00009098464],"genre_scores_gemma":[0.00303793,0.9952652,0.0001886071,0.000166012,0.000136103,0.00005145545,0.0004206868,0.00009741024,0.0006365821],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9885358,"threshold_uncertainty_score":0.9997958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08546710615380751,"score_gpt":0.3794512939914076,"score_spread":0.2939841878376001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}