{"id":"W4398749064","doi":"10.1093/ibd/izae081","title":"Challenges in IBD Research 2024: Preclinical Human IBD Mechanisms","year":2024,"lang":"en","type":"review","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Janssen Biotech; National Institute of Diabetes and Digestive and Kidney Diseases; Pfizer; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Incyte; Merck","keywords":"Medicine; Inflammatory bowel disease; Translational research; Multidisciplinary approach; Prioritization; Inflammatory Bowel Diseases; Disease; Bioinformatics; Management science; Pathology; Biology; Political science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005701059,0.0007080933,0.001364022,0.00176333,0.0004674989,0.002868952,0.001165318,0.002599542,0.005080714],"category_scores_gemma":[0.005539051,0.0003619794,0.0009503515,0.001371215,0.001423174,0.003653894,0.001414129,0.004759654,0.002742744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00178175,"about_ca_system_score_gemma":0.005009764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001358603,"about_ca_topic_score_gemma":0.00228833,"domain_scores_codex":[0.9982334,0.0007252636,0.0001988854,0.0001599465,0.0005547113,0.0001278797],"domain_scores_gemma":[0.9945813,0.003584611,0.0003145226,0.0001949075,0.001072377,0.0002522247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001530639,0.00008192757,0.0002138378,0.02687163,0.0001057902,0.0002210577,0.0001814299,0.0003720433,0.002515134,0.03431895,0.08326504,0.8517002],"study_design_scores_gemma":[0.00001499539,0.0001059951,0.0002548685,0.007651683,0.00006493252,0.000491461,0.00009166153,0.00004928968,0.0004555623,0.005528341,0.9852774,0.00001393925],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001068522,0.9940566,0.0003218777,0.002768635,0.0009336078,0.00001233875,0.00002769754,0.00001427806,0.001758127],"genre_scores_gemma":[0.001029986,0.9946281,0.0006635594,0.00197165,0.0006287657,0.00002292398,0.00005943937,0.000006248223,0.0009894407],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005701059,"threshold_uncertainty_score":0.03015047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1229557494438057,"score_gpt":0.4101900501147616,"score_spread":0.2872343006709559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}