{"id":"W4398761318","doi":"10.1093/ndt/gfae119","title":"Calcineurin inhibitor effects on kidney electrolyte handling and blood pressure: tacrolimus versus voclosporin","year":2024,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Aurinia (Canada)","funders":"","keywords":"Medicine; Calcineurin; Tacrolimus; Pharmacology; Kidney; Urology; Blood pressure; Internal medicine; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001277088,0.0002043556,0.000182099,0.000132196,0.00009365683,0.00003450674,0.00006538266,0.0002688496,0.00001120022],"category_scores_gemma":[0.00001379752,0.0001958194,0.0001058547,0.0001432776,0.00004899055,0.00001169217,0.000005524604,0.0001400491,0.000008613044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000451712,"about_ca_system_score_gemma":0.00004623506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001317958,"about_ca_topic_score_gemma":0.00004618584,"domain_scores_codex":[0.9988506,0.00007376886,0.0002033697,0.000486393,0.0001351623,0.0002506553],"domain_scores_gemma":[0.9996214,0.00005902104,0.00003802369,0.0001502434,0.00003127591,0.0001000309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00246922,0.0000550421,0.0007653793,0.0003290321,0.0006862895,0.00007236973,0.0002543616,0.0003913641,0.99066,0.0002762104,0.0002799868,0.003760725],"study_design_scores_gemma":[0.003667001,0.001307664,0.007121748,0.00006554227,0.002512068,0.00004498152,0.000005446779,0.0008989287,0.9705725,0.00007601471,0.01342422,0.0003038391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995102,0.001921502,0.001584139,0.0003943201,0.0005379753,0.0002181215,0.00003777247,0.00006810296,0.0001360978],"genre_scores_gemma":[0.9960125,0.001313618,0.00006297846,0.0004572879,0.0008500827,0.00004962884,0.001035841,0.00002943707,0.0001886201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02008748,"threshold_uncertainty_score":0.7985284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004855320139128291,"score_gpt":0.2242560122723887,"score_spread":0.2194006921332604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}