{"id":"W4398772127","doi":"10.1126/sciimmunol.ade3814","title":"Heart failure promotes multimorbidity through innate immune memory","year":2024,"lang":"en","type":"article","venue":"Science Immunology","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Innate immune system; Immune system; Heart failure; Inflammation; Immunological memory; Immunology; Biology; Immunity; Medicine; Cardiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0009674538,0.0002673914,0.0003503169,0.0004385453,0.0009068848,0.0001345775,0.0008434838,0.0003017423,0.001726992],"category_scores_gemma":[0.0004267736,0.0002225135,0.0001694386,0.001334609,0.00190047,0.0008212902,0.0004264142,0.0007389977,0.004045523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001381876,"about_ca_system_score_gemma":0.0006231347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003944823,"about_ca_topic_score_gemma":0.00001857262,"domain_scores_codex":[0.9976488,0.0002422126,0.00042572,0.000698714,0.00008395969,0.0009005454],"domain_scores_gemma":[0.9987709,0.0002592692,0.00007238341,0.0006845968,0.0001914383,0.00002141821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005245002,0.00008209523,0.00004753568,0.00001629317,0.00009209599,0.000009734631,0.0008119221,0.000003888025,0.9804121,0.01125378,0.00188222,0.005335846],"study_design_scores_gemma":[0.0007050599,0.0003872983,0.01376381,0.00008800135,0.00003587503,0.0007837536,0.0008224134,0.00007772646,0.6606787,0.001689964,0.320565,0.0004023545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9425175,0.03839973,0.0003341481,0.00870871,0.006587154,0.0005097056,0.00002911078,0.0006428089,0.002271094],"genre_scores_gemma":[0.993665,0.0001407219,0.0006863103,0.0001405683,0.00004062591,0.0000564161,0.00003526279,0.00002500127,0.005210056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3197334,"threshold_uncertainty_score":0.9991856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01746605427053588,"score_gpt":0.2951868418459799,"score_spread":0.2777207875754441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}