{"id":"W4398780476","doi":"10.1101/2024.05.23.595523","title":"Potential Benefits of Ketone Therapy as a Novel Immunometabolic Treatment for Schizophrenia","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Diet and metabolism studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Inflammation; Ketone bodies; Lipopolysaccharide; Ketosis; Pathophysiology; Medicine; Intraperitoneal injection; Pharmacology; Internal medicine; Endocrinology; Metabolism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001954533,0.000288133,0.0004043283,0.0003277686,0.0001491926,0.0003882537,0.0002333195,0.0003586958,0.003552256],"category_scores_gemma":[0.0001354695,0.0000599824,0.0002979445,0.0001611987,0.0002169803,0.0002583037,0.0002704998,0.0006422848,0.0003330875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001952756,"about_ca_system_score_gemma":0.0003275965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005104839,"about_ca_topic_score_gemma":0.001610481,"domain_scores_codex":[0.9999499,0.00001676992,0.00000567472,0.000007035186,0.000008174013,0.00001232612],"domain_scores_gemma":[0.9999161,0.00001824535,0.00002221606,0.00000485948,0.00001224652,0.00002633228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.02302336,0.004961449,0.004537796,0.008914827,0.0005749509,0.001919678,0.0001343148,0.001308743,0.2029223,0.005058688,0.006052187,0.7405918],"study_design_scores_gemma":[0.0239854,0.2030689,0.1636111,0.009426007,0.00425282,0.01180125,0.001941703,0.008090659,0.2139674,0.01965219,0.3397023,0.0005002802],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5526336,0.4203229,0.00348507,0.006325201,0.0009930821,0.0002307529,0.001142341,0.0001954535,0.01467173],"genre_scores_gemma":[0.7871323,0.2004495,0.004131832,0.001636468,0.0004853091,0.0001971663,0.0004844099,0.00001679777,0.005466133],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.003552256,"threshold_uncertainty_score":0.0118835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02433589272076507,"score_gpt":0.2608201351364735,"score_spread":0.2364842424157084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}