{"id":"W4399025892","doi":"10.1101/2024.05.25.595865","title":"A Peptide Derived from Sorting Nexin 1 Inhibits HPV16 Entry, Retrograde Trafficking, and L2 Membrane Spanning","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences","keywords":"Sorting nexin; Peptide; Sorting; Attraction; Cell biology; Chemistry; Biology; Computer science; Biochemistry; Endosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000151456,0.0003136795,0.0002571851,0.0001494818,0.0001537944,0.0001719845,0.0002164976,0.0003123941,0.001236009],"category_scores_gemma":[0.000118428,0.0001065712,0.0002009628,0.0001076967,0.000225077,0.0001459863,0.0001028337,0.0006254298,0.0002794477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001956249,"about_ca_system_score_gemma":0.0003572648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005602054,"about_ca_topic_score_gemma":0.0008059634,"domain_scores_codex":[0.9999151,0.00001950633,0.000007535753,0.00001198323,0.00001677607,0.00002900849],"domain_scores_gemma":[0.9999429,0.00001650915,0.00001182064,0.000006724149,0.000004937814,0.00001721078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008417433,0.0004390065,0.0001346622,0.0000656362,0.000008578083,0.00004642432,0.00002333511,0.0002322394,0.9934117,0.0001583945,0.0001280597,0.004510211],"study_design_scores_gemma":[0.0002769415,0.006090252,0.003223649,0.00001268858,0.00001748317,0.0003027404,0.00002238557,0.001148516,0.9859627,0.00009840819,0.002835657,0.000008592925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965892,0.001255684,0.0005007345,0.00007377076,0.00003667914,0.00003274988,0.0001452782,0.00003540492,0.001330487],"genre_scores_gemma":[0.9944856,0.001392634,0.001171924,0.00006746071,0.00002029072,0.00005151278,0.0005557787,0.00001359678,0.002241313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001236009,"threshold_uncertainty_score":0.004134893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01820504050036699,"score_gpt":0.2500254631019981,"score_spread":0.2318204226016311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}