{"id":"W4399033744","doi":"10.1101/2024.05.24.595859","title":"A cortical locus for modulation of arousal states","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Neural dynamics and brain function","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"NIH Office of the Director; National Institutes of Health; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"Arousal; Optogenetics; Neuroscience; Locus coeruleus; Psychology; Sensory system; Prefrontal cortex; Pupil; Pupillometry; Visual cortex; Pupillary response; Cognition; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009003665,0.0002118928,0.0001744443,0.0001458175,0.000157646,0.000367538,0.0001673814,0.000148372,0.001108221],"category_scores_gemma":[0.0003110188,0.00009953127,0.0002520413,0.00005451546,0.0002692683,0.0001574411,0.000257178,0.0003563527,0.000169132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002243325,"about_ca_system_score_gemma":0.0002754676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005306226,"about_ca_topic_score_gemma":0.0006046246,"domain_scores_codex":[0.9999214,0.00001119772,0.000003577814,0.00002335982,0.00002337729,0.00001705617],"domain_scores_gemma":[0.9998654,0.00003444571,0.00002745408,0.00001916772,0.00002539417,0.00002817083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004372105,0.00001052895,0.0006135949,0.00003572825,0.000007020269,0.00004579782,0.0000303237,0.0001094838,0.9915935,0.0004085451,0.00005006046,0.007051804],"study_design_scores_gemma":[0.00004246133,0.001032617,0.336477,0.00008025105,0.0001061228,0.0008914641,0.0001721423,0.006752158,0.6447617,0.002010463,0.007646342,0.00002722874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9371605,0.001949403,0.04879083,0.0002918721,0.00008543348,0.00009520801,0.0001993071,0.0002927725,0.01113459],"genre_scores_gemma":[0.9928389,0.0004775476,0.005167564,0.00007770291,0.00002019376,0.00005355989,0.00006869229,0.00002252379,0.001273302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001108221,"threshold_uncertainty_score":0.003707409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02201934727652334,"score_gpt":0.2431757769371892,"score_spread":0.2211564296606659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}