{"id":"W4399042762","doi":"10.3390/pharmaceutics16060713","title":"In Vitro and In Vivo Synergetic Radiotherapy with Gold Nanoparticles and Docetaxel for Pancreatic Cancer","year":2024,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Radiation Therapy and Dosimetry","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia; BC Cancer Agency; University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Kuwait Foundation for the Advancement of Sciences; British Columbia Knowledge Development Fund; National Institutes of Health; University of Victoria","keywords":"In vivo; Pancreatic cancer; Spheroid; In vitro; Docetaxel; Radiation therapy; Cancer research; Colloidal gold; Chemistry; Cancer; Medicine; Internal medicine; Oncology; Pharmacology; Nanoparticle; Nanotechnology; Biology; Materials science; Biochemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001455606,0.00009993098,0.0001859027,0.000133614,0.00001549276,0.00002786497,0.00002022609,0.0000352736,0.00003849039],"category_scores_gemma":[0.000009161315,0.00007728056,0.00001514448,0.0002238001,0.0000511192,0.0000924577,0.00000428143,0.0001024074,4.833003e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005942579,"about_ca_system_score_gemma":0.00004288385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002921721,"about_ca_topic_score_gemma":0.00001457928,"domain_scores_codex":[0.999417,0.00002022343,0.0001418439,0.0001731562,0.00007704303,0.0001707334],"domain_scores_gemma":[0.9997271,0.0001138678,0.00001706433,0.00006068479,0.00001137152,0.0000698872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001937424,0.0001000428,0.02994552,0.000790123,0.0001401221,0.00006436151,0.001326885,0.0001047815,0.937992,0.0001369879,0.0006903971,0.02677134],"study_design_scores_gemma":[0.00806272,0.0002236083,0.004409823,0.000376524,0.0002561878,0.00008894063,0.0001374261,0.1734062,0.7473688,0.0002463436,0.06515691,0.0002665586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9402521,0.05670541,0.00006247768,0.002421708,0.00008892691,0.0003902046,0.00001381433,0.00002570582,0.00003960467],"genre_scores_gemma":[0.9864129,0.01046649,0.0008191337,0.00169736,0.00009367926,0.00008914786,0.000001252179,0.00002266261,0.0003973606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1906233,"threshold_uncertainty_score":0.315141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02611186818238136,"score_gpt":0.3536949731608794,"score_spread":0.327583104978498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}