{"id":"W4399045402","doi":"10.1111/bjh.19555","title":"Canadian cancer trials group <scp>LY</scp>.17: A randomized phase <scp>II</scp> study evaluating novel salvage therapy pre‐autologous stem cell transplant in relapsed/refractory diffuse large B‐cell lymphoma—outcome of rituximab‐dose‐intensive cyclophosphamide, etoposide, cisplatin (R‐<scp>DICEP</scp>) versus R‐<scp>GDP</scp>","year":2024,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Manitoba; Hôpital de l'Enfant-Jésus; Juravinski Cancer Centre; Hôpital Maisonneuve-Rosemont; Centre hospitalier universitaire de Québec; University of Calgary; Princess Margaret Cancer Centre; Queen's University; Moncton Hospital; University Health Network; Queen Elizabeth II Health Sciences Centre; University of Alberta","funders":"Canadian Cancer Society; Roche Canada","keywords":"Medicine; Rituximab; Gemcitabine; Autologous stem-cell transplantation; Internal medicine; Etoposide; Salvage therapy; Oncology; Diffuse large B-cell lymphoma; Interim analysis; Cyclophosphamide; Melphalan; Surgery; Lymphoma; Chemotherapy; Urology; Clinical trial","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002192613,0.001668835,0.002082326,0.0003883703,0.00080859,0.0009598305,0.000902874,0.001496884,0.005303253],"category_scores_gemma":[0.001437914,0.0005334241,0.002131283,0.0006607084,0.001091142,0.0003589034,0.0003540674,0.002586386,0.0006616451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004958051,"about_ca_system_score_gemma":0.01604094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.09561674,"about_ca_topic_score_gemma":0.2382328,"domain_scores_codex":[0.9991925,0.0004188966,0.00002791756,0.00009319059,0.0001318702,0.0001356933],"domain_scores_gemma":[0.9990667,0.000129757,0.0001758198,0.00006001706,0.0001202419,0.0004475738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9298992,0.008149896,0.002335724,0.001077272,0.002248365,0.00009641133,0.0001214176,0.001260638,0.005099934,0.0005265574,0.01103767,0.03814704],"study_design_scores_gemma":[0.9482477,0.04055784,0.003962059,0.00005434915,0.0008049626,0.00004346966,0.00002450659,0.0004632374,0.0005977583,0.0001555514,0.005066731,0.00002188491],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9262946,0.009713547,0.001072042,0.004250475,0.0007850236,0.03285711,0.01373368,0.0002124693,0.01108106],"genre_scores_gemma":[0.9165617,0.00759079,0.008501448,0.007898767,0.000699697,0.02712595,0.01427568,0.0001127337,0.01723327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09561674,"threshold_uncertainty_score":0.1901204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04200162874759488,"score_gpt":0.3396762226595803,"score_spread":0.2976745939119854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}