{"id":"W4399053132","doi":"10.3389/fcell.2024.1368171","title":"Emerging role of HDAC11 in skeletal muscle biology","year":2024,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"HDAC11; Biology; Histone; Epigenetics; Histone deacetylase; HDAC4; Histone deacetylase 5; Acetylation; Cell biology; Transcription factor; Promoter; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005640728,0.0004844762,0.0005132273,0.0003631313,0.0002018871,0.001017854,0.0004682385,0.0007976773,0.002723819],"category_scores_gemma":[0.0002646942,0.0001782849,0.0003294334,0.0003455319,0.0008052741,0.001055504,0.0005096039,0.001524958,0.001067016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006223088,"about_ca_system_score_gemma":0.0006585048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004596784,"about_ca_topic_score_gemma":0.001083829,"domain_scores_codex":[0.9998754,0.00001799632,0.000008064733,0.00003852202,0.00003036608,0.00002956477],"domain_scores_gemma":[0.9998096,0.00004287023,0.00002666335,0.00001125993,0.00005943973,0.00005013731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001037026,0.0001793648,0.004573735,0.005428201,0.0001763656,0.001173789,0.0003745803,0.001308181,0.3143886,0.07466501,0.02269671,0.5739984],"study_design_scores_gemma":[0.0001040359,0.0006730374,0.01291797,0.0006586354,0.0001833755,0.002247924,0.0004271875,0.002070949,0.06829938,0.0301047,0.8822495,0.00006329757],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.02802945,0.9308168,0.01139213,0.01137862,0.001216317,0.00002488813,0.0003347102,0.0001625646,0.0166446],"genre_scores_gemma":[0.1746978,0.8008122,0.007569755,0.003290363,0.00188102,0.00005348975,0.0005360494,0.00002725725,0.01113214],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002723819,"threshold_uncertainty_score":0.00911206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004828998062832461,"score_gpt":0.2451183014829938,"score_spread":0.2402893034201613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}