{"id":"W4399053619","doi":"10.1111/imm.13804","title":"T cell‐intrinsic <scp>PKD3</scp> fine‐tunes differentiation into <scp>CD8</scp><sup>+</sup> central memory T cells and <scp>CD8</scp> single positive thymocyte development","year":2024,"lang":"en","type":"article","venue":"Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Austrian Science Fund; Österreichischen Akademie der Wissenschaften","keywords":"Thymocyte; CD8; Biology; Cell biology; T cell; Cytotoxic T cell; Compartment (ship); Lymphopoiesis; Immune system; Immunology; In vitro; Genetics; Haematopoiesis; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008480894,0.0002939684,0.0001785791,0.0001815837,0.0001419739,0.0003277327,0.0001689314,0.0002435326,0.001817464],"category_scores_gemma":[0.00008086779,0.0001129279,0.0002013594,0.0001411701,0.0002995747,0.0001505358,0.0001975049,0.0007194655,0.000505544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002851123,"about_ca_system_score_gemma":0.0001837138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004472751,"about_ca_topic_score_gemma":0.0007797289,"domain_scores_codex":[0.9998765,0.00001785871,0.00001365033,0.00002758816,0.00003086674,0.00003344283],"domain_scores_gemma":[0.9998988,0.00001986899,0.00002976639,0.00001537027,0.000007641798,0.00002854171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008296119,0.00001180181,0.00007873867,0.00001717577,0.000002138089,0.00002922391,0.000003685538,0.00004986192,0.9992384,0.00004385285,0.0000268352,0.0004154628],"study_design_scores_gemma":[0.00001607176,0.0001393315,0.002191724,0.000003562002,0.000008929937,0.0001565225,0.00001739014,0.0006103936,0.9950905,0.00003507148,0.001727571,0.000003068056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948409,0.000596819,0.002135783,0.00009447336,0.00003160501,0.00001941806,0.0007101674,0.0001227042,0.001448252],"genre_scores_gemma":[0.9961401,0.0002586892,0.0009990296,0.0000379716,0.000007920435,0.00002348643,0.0004425171,0.00003908805,0.002051286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001817464,"threshold_uncertainty_score":0.006080031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007505717622116484,"score_gpt":0.2017387875043751,"score_spread":0.1942330698822586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}