{"id":"W4399053619","doi":"10.1111/imm.13804","title":"T cell‐intrinsic <scp>PKD3</scp> fine‐tunes differentiation into <scp>CD8</scp><sup>+</sup> central memory T cells and <scp>CD8</scp> single positive thymocyte development","year":2024,"lang":"en","type":"article","venue":"Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Austrian Science Fund; Österreichischen Akademie der Wissenschaften","keywords":"Thymocyte; CD8; Biology; Cell biology; T cell; Cytotoxic T cell; Compartment (ship); Lymphopoiesis; Immune system; Immunology; In vitro; Genetics; Haematopoiesis; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003955351,0.001012396,0.001026297,0.0009297127,0.0008741894,0.0002878911,0.0005583109,0.00128163,0.0003479597],"category_scores_gemma":[0.0005538395,0.0009840596,0.0003894016,0.0005741952,0.000625779,0.0007033105,0.0005514433,0.001624273,0.003528914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006149131,"about_ca_system_score_gemma":0.0003350689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002952823,"about_ca_topic_score_gemma":0.00005846428,"domain_scores_codex":[0.9945496,0.0008559096,0.001289648,0.001427043,0.0001860996,0.001691716],"domain_scores_gemma":[0.9961721,0.002210367,0.0004560252,0.0007030545,0.0003297369,0.0001286762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006452513,0.0006907611,0.0006339487,0.0001798724,0.001559796,0.00005704305,0.01558085,0.00007248498,0.9138028,0.0003505533,0.04496708,0.02204029],"study_design_scores_gemma":[0.001766351,0.0006168471,0.008954867,0.0001784971,0.0002533995,0.0002605204,0.006914706,0.0001212474,0.6761209,0.0001170557,0.3045428,0.0001528231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9430199,0.03615445,0.001277564,0.0001846288,0.01192809,0.0008591469,0.00004354303,0.0006325322,0.005900139],"genre_scores_gemma":[0.9392962,0.001868597,0.000244671,0.0004303428,0.0003027769,0.0001544879,0.001280946,0.0001533012,0.05626861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2595757,"threshold_uncertainty_score":0.999261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007505717622116484,"score_gpt":0.2017387875043751,"score_spread":0.1942330698822586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}