{"id":"W4399053624","doi":"10.1101/2024.05.22.595308","title":"<i>GTP cyclohydrolase II</i> ( <i>gch2</i> ) and axanthism in ball pythons: a new vertebrate model for pterin-based pigmentation","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vanier College; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Pterin; Vertebrate; GTP'; Zoology; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003334932,0.0005204817,0.0003740519,0.0002134829,0.0001055549,0.0001547302,0.0002757806,0.0005233125,0.000004681631],"category_scores_gemma":[0.00008632823,0.0005789115,0.0001429889,0.000190046,0.00007603061,0.00001055862,0.0005172131,0.0003179021,0.000008148072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007678356,"about_ca_system_score_gemma":0.001091386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003163229,"about_ca_topic_score_gemma":0.00002744274,"domain_scores_codex":[0.9977414,0.00004782624,0.000468687,0.001094276,0.00019221,0.0004556008],"domain_scores_gemma":[0.9989365,0.00001669124,0.0001802987,0.0005283171,0.0001170675,0.0002210954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002670446,0.000105396,0.001510858,0.000648807,0.00009518822,0.00001588468,0.00002596902,0.002003681,0.9915793,0.0001888041,0.003546668,0.00001240652],"study_design_scores_gemma":[0.004351196,0.0003542745,0.002840853,0.0009668288,0.000256471,6.219929e-8,0.000008571546,0.1603456,0.8155834,0.0001877471,0.0129331,0.002171927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832761,0.003170669,0.01096553,0.0006594146,0.0005149833,0.001086795,0.0002122095,0.00009510447,0.00001919384],"genre_scores_gemma":[0.9868326,0.0006644002,0.01081863,0.0009122228,0.0001859154,0.0003866315,0.00001080881,0.0001285058,0.0000602725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1759959,"threshold_uncertainty_score":0.9996662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01042449612604601,"score_gpt":0.2246148460840429,"score_spread":0.2141903499579969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}