{"id":"W4399105858","doi":"10.1021/acs.jnatprod.4c00248","title":"Tetrahydroxanthene-1,3(2<i>H</i>)-diones and Oxidized Hexadiene Derivatives from <i>Uvaria leptopoda</i> and Their Biological Activities","year":2024,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Traditional and Medicinal Uses of Annonaceae","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Thailand Science Research and Innovation; National Research Council of Thailand; Mae Fah Luang University","keywords":"Phytochemical; Cycloaddition; Cyclobutane; Stereochemistry; Chemistry; Annonaceae; Mass spectrometry; Twig; Ring (chemistry); Organic chemistry; Biology; Chromatography; Botany; Biochemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004350836,0.0002357464,0.00008321862,0.0002334942,0.00009096152,0.0001479732,0.00009140958,0.0001216922,0.00137828],"category_scores_gemma":[0.00004458892,0.000095572,0.000121754,0.0002231345,0.000116608,0.0001518185,0.00009639675,0.0002474869,0.0001671077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001060883,"about_ca_system_score_gemma":0.00009998494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004620258,"about_ca_topic_score_gemma":0.000856837,"domain_scores_codex":[0.9999713,0.000003684198,0.00000213838,0.000008314726,0.000007110566,0.000007374375],"domain_scores_gemma":[0.999962,0.000005529024,0.00001194694,0.000003862687,0.00000584514,0.00001082314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006499889,0.000005238003,0.0001491744,0.00001866435,0.000002329214,0.00002198074,0.000008987146,0.00001800419,0.9990017,0.00001528994,0.000006519024,0.0006871002],"study_design_scores_gemma":[0.00001184462,0.0003178831,0.02517244,0.000006487263,0.00001732169,0.0001894887,0.0000525812,0.0001948316,0.9721209,0.00004788139,0.001862939,0.000005536407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995087,0.001210531,0.001456203,0.00003946158,0.000007412999,0.00002248239,0.0007872448,0.00002975517,0.001360021],"genre_scores_gemma":[0.9917136,0.0009800858,0.002624525,0.00004137563,0.000006995575,0.00002248227,0.001558774,0.000009523922,0.003042692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00137828,"threshold_uncertainty_score":0.004610777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01115620095057926,"score_gpt":0.2265132544015528,"score_spread":0.2153570534509735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}