{"id":"W4399105858","doi":"10.1021/acs.jnatprod.4c00248","title":"Tetrahydroxanthene-1,3(2<i>H</i>)-diones and Oxidized Hexadiene Derivatives from <i>Uvaria leptopoda</i> and Their Biological Activities","year":2024,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Traditional and Medicinal Uses of Annonaceae","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Thailand Science Research and Innovation; National Research Council of Thailand; Mae Fah Luang University","keywords":"Phytochemical; Cycloaddition; Cyclobutane; Stereochemistry; Chemistry; Annonaceae; Mass spectrometry; Twig; Ring (chemistry); Organic chemistry; Biology; Chromatography; Botany; Biochemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001771023,0.0001538696,0.0002189446,0.00005942395,0.0000638842,0.0000474555,0.00009764997,0.00008480513,0.000004866321],"category_scores_gemma":[0.0001765706,0.00009283455,0.00006206649,0.00007365902,0.0002203525,0.00003039557,0.00005806485,0.0002324303,4.979379e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008197066,"about_ca_system_score_gemma":0.0000657924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005310336,"about_ca_topic_score_gemma":0.000002021563,"domain_scores_codex":[0.999252,0.00005597835,0.0002019312,0.0002463951,0.0001053274,0.0001383553],"domain_scores_gemma":[0.9995853,0.0000926749,0.00008399435,0.00008153575,0.00008241395,0.00007403646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002545735,0.00003116408,0.0001520369,0.00003142518,0.0001397001,0.00002633687,0.0001847016,6.582252e-7,0.990766,0.0001251299,0.001710429,0.006577798],"study_design_scores_gemma":[0.000763972,0.0009797738,0.0173156,0.00022846,0.00004973604,0.001088539,0.0004988026,0.00001615649,0.8994383,0.003126379,0.07622062,0.0002736498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9307681,0.06444615,0.00003402017,0.003906092,0.0007052721,0.00006197413,0.00003093758,0.00000929816,0.0000381449],"genre_scores_gemma":[0.9921271,0.005040457,0.0009833827,0.0002573852,0.001427192,0.0000012137,0.00002799345,0.00001072839,0.0001245174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09132774,"threshold_uncertainty_score":0.3785683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01115620095057926,"score_gpt":0.2265132544015528,"score_spread":0.2153570534509735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}