{"id":"W4399125784","doi":"10.14740/jocmr5165","title":"Efficacy and Safety of Upadacitinib Plus Intensive Granulocyte and Monocyte Adsorptive Apheresis as Induction for Intractable Ulcerative Colitis","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Medicine Research","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Apheresis; Ulcerative colitis; Monocyte; Granulocyte; Pharmacology; Immunology; Gastroenterology; Internal medicine; Platelet","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004731076,0.000245394,0.001015082,0.000254106,0.0002026764,0.0003267758,0.0002157961,0.0001732104,0.0004100669],"category_scores_gemma":[0.0005176078,0.0001318603,0.0003674673,0.0003147685,0.0002588352,0.0002197098,0.0002089438,0.0006027567,0.0001263813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003169366,"about_ca_system_score_gemma":0.0001959628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001880992,"about_ca_topic_score_gemma":0.0004746626,"domain_scores_codex":[0.9997075,0.000125754,0.00003034229,0.00004356598,0.00005718596,0.00003549126],"domain_scores_gemma":[0.9996541,0.00007944968,0.0001221971,0.00004496812,0.00001531257,0.00008406994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1144664,0.009097036,0.104176,0.0007699488,0.001498179,0.00243294,0.000320741,0.002665073,0.2196894,0.0001967309,0.0009207525,0.5437669],"study_design_scores_gemma":[0.01778721,0.3233472,0.5841938,0.0001620885,0.001659176,0.01283913,0.000186319,0.005227607,0.0484566,0.0001860825,0.00586618,0.00008869354],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975556,0.0018182,0.0001401583,0.00002290674,0.000005565621,0.00002355245,0.00002811425,0.00001378656,0.0003920694],"genre_scores_gemma":[0.9991738,0.0004120548,0.0001778582,0.00002822285,0.00001842453,0.00001739854,0.00008059332,0.000002276787,0.00008920969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001015082,"threshold_uncertainty_score":0.002502084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09700469423787055,"score_gpt":0.4672202486540785,"score_spread":0.370215554416208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}