{"id":"W4399127044","doi":"10.7150/thno.93973","title":"Theranostic digital twins: Concept, framework and roadmap towards personalized radiopharmaceutical therapies","year":2024,"lang":"en","type":"review","venue":"Theranostics","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo; BC Cancer Agency; University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Computer science; Nanotechnology; Medicine; Medical physics; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001503078,0.0008619031,0.002060062,0.00009963043,0.00009267287,0.0002706801,0.00029563,0.0007258773,0.0002648814],"category_scores_gemma":[0.0002701993,0.0005974792,0.0006872027,0.000433829,0.0009501996,0.00007243975,0.0001030193,0.001771178,0.0001586887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001414966,"about_ca_system_score_gemma":0.0004252293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001191144,"about_ca_topic_score_gemma":1.893738e-8,"domain_scores_codex":[0.9974087,0.00009208589,0.0007294876,0.0007782605,0.0004571155,0.000534287],"domain_scores_gemma":[0.9977319,0.0009529341,0.0001345389,0.0005765245,0.00008054152,0.0005236046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000871865,0.0002035197,0.000002802022,0.0148452,0.001727788,0.0002019613,0.0006355132,1.782516e-7,0.00004547925,0.006113318,0.001045645,0.9750914],"study_design_scores_gemma":[0.0006786064,0.0000972636,0.000001931098,0.009863743,0.006812279,0.0006882931,0.00006572148,0.00006067976,0.00003302011,0.001698627,0.9794179,0.0005819703],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005435263,0.9942275,0.0007547935,0.0008552104,0.0003037272,0.001668884,0.0003603751,0.0008125163,0.0009626581],"genre_scores_gemma":[0.001688023,0.9933944,0.0005534655,0.0006524007,0.001368646,0.0002846131,0.000191363,0.0003910103,0.001476095],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9783722,"threshold_uncertainty_score":0.9996477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09015337340036733,"score_gpt":0.4249242555061545,"score_spread":0.3347708821057872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}