{"id":"W4399133791","doi":"10.21037/map-24-ab073","title":"AB073. SOH24AB_228. Immunomodulatory effect of epigenetic modification on T cell phenotype and checkpoint receptor expression in oesophageal adenocarcinoma","year":2024,"lang":"en","type":"article","venue":"Mesentery and Peritoneum","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Epigenetics; Phenotype; Cancer research; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002544163,0.0003606253,0.0003910977,0.0002686567,0.000243288,0.0002816147,0.0003030737,0.0003974631,0.01221508],"category_scores_gemma":[0.00009262539,0.0001546791,0.0002841425,0.0002759071,0.0001775463,0.0001276317,0.0002042894,0.0007433238,0.003488745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003058731,"about_ca_system_score_gemma":0.0005442727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00119159,"about_ca_topic_score_gemma":0.001659763,"domain_scores_codex":[0.9998559,0.00002418963,0.00001187006,0.00002022037,0.00003605125,0.00005179047],"domain_scores_gemma":[0.9999514,0.000004637439,0.000007467645,0.000005794079,0.000007511315,0.00002323419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008369848,0.001932678,0.002333343,0.0004923388,0.00008937608,0.0007334211,0.00003988274,0.0004084865,0.9268799,0.000345524,0.00943658,0.04893869],"study_design_scores_gemma":[0.006359954,0.02838578,0.06416531,0.0001100975,0.0003169743,0.006749192,0.0001878935,0.004197563,0.7327409,0.0004455057,0.1562885,0.00005237951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9608934,0.01361797,0.001072051,0.00116279,0.0007477612,0.0003456002,0.005121285,0.0006037989,0.01643543],"genre_scores_gemma":[0.954055,0.006884065,0.002066732,0.0006844982,0.0002294426,0.0004688211,0.01077685,0.00007330615,0.02476136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01221508,"threshold_uncertainty_score":0.04086351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01047155256236094,"score_gpt":0.2659507681958198,"score_spread":0.2554792156334589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}