{"id":"W4399244117","doi":"10.1016/j.kjs.2024.100265","title":"Investigating emodin derivatives against SARS-CoV-2 found in medicinal herbs","year":2024,"lang":"en","type":"article","venue":"Kuwait Journal of Science","topic":"Phytochemistry and biological activity of medicinal plants","field":"Agricultural and Biological Sciences","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Emodin; Traditional medicine; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Medicinal herbs; Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Virology; Medicine; Chemistry; Chromatography; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001757619,0.000124976,0.0002284511,0.00004988151,0.0001688169,0.000120627,0.0005755743,0.00006311962,0.00002269825],"category_scores_gemma":[0.0008342121,0.00004284599,0.00006125947,0.001261963,0.001135136,0.0006109716,0.00007579621,0.000418869,0.000007381972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007111858,"about_ca_system_score_gemma":0.00009615061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003257389,"about_ca_topic_score_gemma":0.00003299642,"domain_scores_codex":[0.9984041,0.00005031112,0.0003674461,0.0002485957,0.0006034631,0.0003261227],"domain_scores_gemma":[0.99918,0.0003903917,0.0001513516,0.0000303444,0.0001135137,0.0001344535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001131274,0.00003701653,0.002420511,0.00001628323,0.000003652826,0.0000930393,0.0001737223,0.000004958593,0.9490916,0.0000462879,0.0001788846,0.04792279],"study_design_scores_gemma":[0.0003621655,0.001196685,0.2575929,0.002890094,0.00001523226,0.0007670668,0.002224557,0.001621544,0.714368,0.01315444,0.005363055,0.0004441889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951737,0.0007144629,0.00001056025,0.002438863,0.0002565436,0.0000508313,0.000003498853,0.00001648539,0.001335051],"genre_scores_gemma":[0.998726,0.00005238142,0.0002298175,0.0005646924,0.0004069772,8.330223e-7,0.000001097882,4.608626e-7,0.00001780804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2551724,"threshold_uncertainty_score":0.4182457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06258011885127554,"score_gpt":0.3012557608195366,"score_spread":0.2386756419682611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}