{"id":"W4399264501","doi":"10.1016/j.mcpro.2024.100793","title":"Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2","year":2024,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Office of the Director; University of Toronto; Chinese Academy of Sciences; Ministerstvo Školství, Mládeže a Tělovýchovy; Georgetown University; European Commission; National Cancer Research Institute","keywords":"Spheroid; Chemistry; Extracellular; Matrigel; Chondroitin sulfate; Cell culture; In vitro; Plasma protein binding; Heparan sulfate; Cell biology; Biochemistry; Biophysics; Cell; Glycosaminoglycan; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000898485,0.0005372114,0.0003285691,0.0003338756,0.0002744767,0.0004287451,0.0005378562,0.0004587259,0.0002144485],"category_scores_gemma":[0.0002341024,0.0005583962,0.0003731941,0.0006465805,0.0001742563,0.00002704398,0.0003455947,0.0006683754,0.0005554282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001006471,"about_ca_system_score_gemma":0.0003784983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000041517,"about_ca_topic_score_gemma":0.00001367751,"domain_scores_codex":[0.996264,0.0003064954,0.0005831392,0.001236201,0.0006824275,0.000927774],"domain_scores_gemma":[0.9983654,0.00001378669,0.0001045375,0.0009835133,0.000177449,0.0003553158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001331217,0.0001055149,0.00003709517,0.0002290952,0.0001197637,0.0005962668,0.00004885744,0.0001162735,0.9945232,0.001491621,0.0006868634,0.001912339],"study_design_scores_gemma":[0.0006712615,0.0003036787,0.000003689772,0.0001309689,0.00003122016,0.00009782299,0.0000302737,0.001541515,0.9212016,0.0002691708,0.07512332,0.0005954109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.943095,0.006327326,0.04574038,0.0004120681,0.0002398979,0.002418216,0.00007940581,0.0001693721,0.001518359],"genre_scores_gemma":[0.9806337,0.00008586913,0.00604064,0.00007880127,0.0003287703,0.0005016947,0.0009569867,0.0001958503,0.01117768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07443646,"threshold_uncertainty_score":0.9996868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068086725101025,"score_gpt":0.2574307729038823,"score_spread":0.246749905652872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}