{"id":"W4399272814","doi":"10.1101/2024.05.29.596491","title":"Evaluating methods for B-cell clonal family assignment","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"National Institutes of Health","keywords":"Computational biology; Computer science; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01159712,0.001052244,0.0009884523,0.001995083,0.0008080293,0.001312415,0.002234114,0.001745798,0.00409342],"category_scores_gemma":[0.04102706,0.0005100457,0.001251531,0.001052394,0.0009525533,0.001739145,0.002005269,0.001406575,0.0006153528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001468974,"about_ca_system_score_gemma":0.001341939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002778855,"about_ca_topic_score_gemma":0.00245056,"domain_scores_codex":[0.9955153,0.002147467,0.00022732,0.0005568611,0.001330858,0.0002223627],"domain_scores_gemma":[0.9604616,0.03205244,0.001537464,0.002383327,0.003144381,0.0004208322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005285595,0.0001479792,0.01292029,0.0004889197,0.000384646,0.00008434407,0.0001602289,0.7626898,0.006228912,0.01470394,0.001838611,0.1998237],"study_design_scores_gemma":[0.00003294533,0.0001316915,0.001063822,0.00004075536,0.00002806714,0.00005198224,0.00003390384,0.9856806,0.004001724,0.007912166,0.001005197,0.00001712382],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.147259,0.001897497,0.8429714,0.0003782214,0.0001711783,0.0002537438,0.0004677668,0.002788519,0.003812762],"genre_scores_gemma":[0.3999511,0.0003959921,0.5959826,0.0001565444,0.00006631389,0.0003150359,0.000838277,0.0007666229,0.00152755],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01159712,"threshold_uncertainty_score":0.06133211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04044099544430921,"score_gpt":0.3142855665400012,"score_spread":0.273844571095692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}