{"id":"W4399272829","doi":"10.1080/14786419.2024.2359545","title":"Biological activity of natural 2-quinolinones","year":2024,"lang":"en","type":"review","venue":"Natural Product Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Traditional medicine; Natural (archaeology); Chemistry; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.003398513,0.0006199825,0.001764143,0.0007307191,0.0003319899,0.00007043862,0.001189301,0.0008822104,0.0003909072],"category_scores_gemma":[0.0006878941,0.0003801787,0.0007925416,0.00159701,0.001331142,0.0001272006,0.001033014,0.009832123,0.000688772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002582062,"about_ca_system_score_gemma":0.000569779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002941811,"about_ca_topic_score_gemma":0.000005802963,"domain_scores_codex":[0.99321,0.003155475,0.0006368581,0.001225813,0.0006918493,0.001080042],"domain_scores_gemma":[0.9974932,0.0009660888,0.000233326,0.0005591622,0.0005502266,0.0001979892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001472315,0.0003300403,0.0000149086,0.01427731,0.0006697683,0.0001326224,0.00004443997,6.871726e-8,0.001644933,0.0004998352,0.02032967,0.9619092],"study_design_scores_gemma":[0.0001737907,0.0001458968,0.0000387394,0.001979648,0.0003910633,0.0001091071,0.000009705567,0.00002419678,0.001837582,0.0001618205,0.9947215,0.0004069669],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00357861,0.9874743,1.835912e-7,0.0003581895,0.005623588,0.001491089,0.0001730271,0.0001074542,0.001193554],"genre_scores_gemma":[0.1020047,0.8905827,0.00002939513,0.0000244001,0.001634638,0.00009151119,0.0001121003,0.00005485186,0.005465744],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9743918,"threshold_uncertainty_score":0.999865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6530271364491884,"score_gpt":0.6378939548721546,"score_spread":0.01513318157703381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}