{"id":"W4399281523","doi":"10.1200/jco.2024.42.16_suppl.10057","title":"The role of immune checkpoint blockade in children, adolescents, and young adults: A systematic review and meta-analysis.","year":2024,"lang":"en","type":"review","venue":"Journal of Clinical Oncology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Blockade; Meta-analysis; Immune checkpoint; Immune system; Oncology; Immunology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01063111,0.002239657,0.01612154,0.007241456,0.0004995329,0.00256844,0.001677522,0.001793793,0.003449479],"category_scores_gemma":[0.02202135,0.001176206,0.03209085,0.008998776,0.0004964531,0.00170745,0.00126096,0.001484831,0.0002963298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00198318,"about_ca_system_score_gemma":0.003484856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006170629,"about_ca_topic_score_gemma":0.01489034,"domain_scores_codex":[0.9934961,0.002611696,0.00227398,0.0006496324,0.0007297604,0.0002389071],"domain_scores_gemma":[0.988245,0.008227727,0.002219787,0.000313031,0.0008226178,0.0001718529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001561734,0.0000264416,0.004346802,0.5111482,0.4654603,0.0001289222,0.00006914831,0.0004601476,0.0001967723,0.0001355962,0.0008907158,0.0155751],"study_design_scores_gemma":[0.0005585504,0.0001844961,0.004506381,0.04057676,0.9509054,0.0001166274,0.00004841451,0.0001659378,0.0001004736,0.0001674122,0.002647475,0.00002207309],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002430507,0.9960239,0.0003034274,0.0001318516,0.00007605969,0.0002205619,0.0006282711,0.00001212329,0.0001731332],"genre_scores_gemma":[0.1067099,0.8877223,0.001983925,0.0007306253,0.0001834968,0.001258358,0.001106768,0.00002158659,0.0002829884],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01612154,"threshold_uncertainty_score":0.05622339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05968354540550545,"score_gpt":0.4016385193270579,"score_spread":0.3419549739215524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}