{"id":"W4399282355","doi":"10.3390/nutraceuticals4020018","title":"Rapid Immune Modulation after Consuming Euglena gracilis Whole Algae Involving Altered Responses to Ex Vivo Immune Challenges: A Placebo-Controlled Cross-Over Trial","year":2024,"lang":"en","type":"article","venue":"Nutraceuticals","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dover (Canada)","funders":"","keywords":"Ex vivo; Euglena gracilis; Immune system; Immune modulation; Placebo; In vivo; Biology; Algae; Immunology; Medicine; Botany; Pathology; Biochemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.002307568,0.0005375249,0.001049646,0.0006557765,0.0004418409,0.0003281507,0.00039375,0.0006917633,0.003031006],"category_scores_gemma":[0.001900157,0.0004753263,0.0006144328,0.0003989837,0.0002246051,0.000470805,0.000232079,0.0007625086,0.001763681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001925571,"about_ca_system_score_gemma":0.0002073874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000570024,"about_ca_topic_score_gemma":0.00002173835,"domain_scores_codex":[0.995405,0.001194918,0.001403071,0.0008733582,0.0001662426,0.000957437],"domain_scores_gemma":[0.9955864,0.003070815,0.000176585,0.0008456385,0.0002207129,0.00009985096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.3310454,0.0005319833,0.00006116289,0.0001956346,0.0011,0.00005513601,0.003054612,0.00002175402,0.6307521,0.003465911,0.0008217635,0.02889458],"study_design_scores_gemma":[0.2856186,0.002792696,0.05723578,0.001851982,0.0009884781,0.000278632,0.001725709,0.002310084,0.09892964,0.001608969,0.5441216,0.002537891],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8295961,0.1602727,0.0003513625,0.003191409,0.002863833,0.002561588,0.000167954,0.0003720091,0.0006230843],"genre_scores_gemma":[0.9830992,0.001874365,0.0001527346,0.0001875694,0.000248062,0.0008386438,0.00007276845,0.00008622896,0.01344045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5432998,"threshold_uncertainty_score":0.9997699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04091679919155138,"score_gpt":0.3304779524633292,"score_spread":0.2895611532717778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}