{"id":"W4399298496","doi":"10.3390/cancers16112121","title":"Genetic Prognostic Factors in Adult Diffuse Gliomas: A 10-Year Experience at a Single Institution","year":2024,"lang":"en","type":"article","venue":"Cancers","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"IDH1; Glioma; Internal medicine; Proportional hazards model; Oncology; Medicine; Methyltransferase; Retrospective cohort study; Radiation therapy; Gastroenterology; Biology; Pathology; Cancer research; Methylation; Mutant; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005077285,0.0004036766,0.0003571124,0.0005686968,0.0003831836,0.0004402798,0.0002420652,0.0002434268,0.0004746925],"category_scores_gemma":[0.001073441,0.0002060329,0.0002644009,0.001089084,0.000301131,0.0003557625,0.000456464,0.0002894336,0.0002310509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004946902,"about_ca_system_score_gemma":0.0005736267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004246357,"about_ca_topic_score_gemma":0.00546015,"domain_scores_codex":[0.9997184,0.00006161423,0.00004181467,0.00006822572,0.00005260042,0.00005733796],"domain_scores_gemma":[0.9994159,0.00008937847,0.0002017882,0.00004702079,0.00007441085,0.000171476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0000984202,0.0001074223,0.9850868,0.00001665221,0.00002074359,0.001983024,0.0004251256,0.00006572688,0.000374204,0.00001254877,0.0001747876,0.01163469],"study_design_scores_gemma":[0.00002229987,0.000906744,0.9821448,0.00002904516,0.00005235123,0.0135363,0.001535172,0.0003561123,0.0003642663,0.00003702976,0.0009959476,0.00001994031],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991876,0.0004815147,0.00008354106,0.00002806392,0.000002145329,0.000005251705,0.00005171579,0.000004415715,0.000155691],"genre_scores_gemma":[0.9984855,0.0009059933,0.0002247286,0.00003037754,0.00001112077,0.00000673895,0.0001955499,0.0000041403,0.0001359548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004246357,"threshold_uncertainty_score":0.008443296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02151133182258737,"score_gpt":0.2718773099985357,"score_spread":0.2503659781759483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}