{"id":"W4399299943","doi":"10.1038/s44161-024-00480-6","title":"A self-reinforcing cycle hypothesis in heart failure pathogenesis","year":2024,"lang":"en","type":"review","venue":"Nature Cardiovascular Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Pathogenesis; Heart failure; Medicine; Psychology; Cardiology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001083674,0.001182151,0.001455618,0.001274863,0.0003331422,0.001389209,0.001743145,0.002228915,0.003360123],"category_scores_gemma":[0.0009412962,0.0002099247,0.0003867504,0.001444917,0.001244616,0.0018664,0.001164486,0.003225981,0.002135025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001079813,"about_ca_system_score_gemma":0.001252922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009604411,"about_ca_topic_score_gemma":0.001625492,"domain_scores_codex":[0.9998401,0.00004027739,0.00001855641,0.0000316115,0.00005044806,0.0000189709],"domain_scores_gemma":[0.9996806,0.0001652431,0.00002967764,0.0000127558,0.00007353487,0.00003817257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001292215,0.0000683973,0.0002150412,0.008556579,0.0001111267,0.0005057225,0.00006947572,0.0007106664,0.001737377,0.02832258,0.07235944,0.8872144],"study_design_scores_gemma":[0.00004306729,0.00007730805,0.0006293218,0.002753964,0.0001077781,0.001244998,0.00007071658,0.0002197269,0.0003774773,0.02050177,0.9739449,0.0000291054],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006830801,0.9967644,0.0004777519,0.001025948,0.0007185516,0.000004527597,0.00001501987,0.00001188458,0.0009136661],"genre_scores_gemma":[0.0008572914,0.9963134,0.0003642571,0.0006547776,0.0008444467,0.000009727505,0.00002842175,0.000002466752,0.0009252004],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003360123,"threshold_uncertainty_score":0.01124072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04171727491178873,"score_gpt":0.3508773399694626,"score_spread":0.3091600650576738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}