{"id":"W4399303735","doi":"10.7554/elife.93260.2.sa0","title":"Reviewer #3 (Public Review): Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McMaster University; Canadian Institutes of Health Research; Hamilton Health Sciences; Partenariat Canadien Contre Le Cancer; Heart and Stroke Foundation of Canada","keywords":"Offspring; DNA methylation; Public health; Demography; Medicine; Genetics; Environmental health; Biology; Pregnancy; Gene; Pathology; Sociology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.05055885,0.001823962,0.006054853,0.005217868,0.003017251,0.007708133,0.007082264,0.01850199,0.06474763],"category_scores_gemma":[0.3080033,0.002035872,0.005658838,0.004377728,0.002904104,0.005128092,0.003763356,0.006090642,0.01688131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007123549,"about_ca_system_score_gemma":0.01578245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007936597,"about_ca_topic_score_gemma":0.010442,"domain_scores_codex":[0.9637858,0.01264631,0.009944577,0.003110293,0.009212237,0.001300679],"domain_scores_gemma":[0.7289286,0.05985666,0.02891364,0.009803698,0.1675656,0.004931882],"domain_codex":null,"domain_gemma":"evaluation","domain_candidate":"evaluation","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001691186,0.000009150976,0.0004175481,0.02323785,0.0002731382,0.0001077088,0.000113743,0.00004287748,0.00008917542,0.0002200837,0.966072,0.009247489],"study_design_scores_gemma":[0.001867217,0.0001129084,0.005486848,0.08655222,0.001864486,0.0008400498,0.0005791346,0.0005807684,0.0006053414,0.003029619,0.8982449,0.0002366422],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001053722,0.04939214,0.002938249,0.4538566,0.4535545,0.00646485,0.02341253,0.001339134,0.00798834],"genre_scores_gemma":[0.02298864,0.05000117,0.005999506,0.6750137,0.1768223,0.02740986,0.006918177,0.001776156,0.03307046],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.9494411,"threshold_uncertainty_score":0.2673839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04460252443827665,"score_gpt":0.3190635478350913,"score_spread":0.2744610233968147,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}