{"id":"W4399311202","doi":"10.1039/d4an00432a","title":"Ultrasensitive electrochemical immunosensor for the detection of C-reactive protein antigen","year":2024,"lang":"en","type":"article","venue":"The Analyst","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Electrochemistry; Chemistry; Antigen; Chromatography; Medicine; Electrode; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002467301,0.0001046268,0.0001172245,0.00003290421,0.000108575,0.00001977689,0.0001196588,0.00007322069,4.825693e-7],"category_scores_gemma":[0.00007639553,0.00005428103,0.000221064,0.0001986636,0.0001474348,0.000002560833,0.00002533554,0.00009524406,0.000001046376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001331368,"about_ca_system_score_gemma":0.00002308869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002675759,"about_ca_topic_score_gemma":0.00003313609,"domain_scores_codex":[0.9993782,0.0000473313,0.0001474097,0.0002055062,0.00008543617,0.0001361042],"domain_scores_gemma":[0.9994467,0.00007414097,0.00006372981,0.000277824,0.0001237424,0.00001386646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001506704,0.00001256851,0.000003227633,0.000007656283,0.000360792,5.306425e-7,0.00002396258,0.000001962156,0.9954101,0.00005212946,0.00005315393,0.003923281],"study_design_scores_gemma":[0.00005316026,0.0001361267,0.00005837018,0.00001575279,0.0001602288,0.00001225277,0.0001335313,0.000899852,0.9932435,0.0001977205,0.005010935,0.00007864355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8749415,0.0019974,0.1218644,0.0005313313,0.00003250342,0.0004441532,0.00002690453,0.00003887708,0.0001229368],"genre_scores_gemma":[0.9989204,0.0001077171,0.0003927663,0.00004720262,0.0001727144,0.00002502119,0.00003643344,0.00001288924,0.0002847979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.123979,"threshold_uncertainty_score":0.2213516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006542602993398113,"score_gpt":0.2661429410206626,"score_spread":0.2596003380272645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}