{"id":"W4399359713","doi":"10.1016/j.prp.2024.155388","title":"The science of exosomes: Understanding their formation, capture, and role in cellular communication","year":2024,"lang":"en","type":"article","venue":"Pathology - Research and Practice","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Microvesicles; Cell biology; Biology; Microvesicle; Multicellular organism; Cell type; Exosome; Endocytosis; Cell; Cancer cell; Inflammation; Angiogenesis; Cancer; Immunology; Cancer research; microRNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004879456,0.00005348105,0.00005178758,0.00009676211,0.0003012773,0.0001012747,0.0002050703,0.00006196013,0.000001526812],"category_scores_gemma":[0.001884853,0.00003548528,0.00001054697,0.0002414284,0.001294534,0.00004713201,0.0002703044,0.0002301681,0.000001263558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000248107,"about_ca_system_score_gemma":0.0001197812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001768001,"about_ca_topic_score_gemma":0.00003693138,"domain_scores_codex":[0.9987696,0.0005530303,0.0001303132,0.0001927535,0.0001494469,0.0002048758],"domain_scores_gemma":[0.9986501,0.00082821,0.00003529742,0.0003108031,0.0001212182,0.0000543779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001436806,0.00003951473,0.0002260075,0.00005530721,0.000009968654,0.00002255052,0.001498765,0.000002281161,0.9726403,0.02312882,0.0001352301,0.002097543],"study_design_scores_gemma":[0.000831724,0.0006820335,0.001440262,0.0001710951,0.00003142619,0.0007158692,0.07905044,0.00380329,0.7081504,0.1654652,0.03932895,0.0003293137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9063225,0.08282933,0.001575385,0.002781638,0.0000433639,0.0002428639,0.00001025326,0.000006579816,0.006188095],"genre_scores_gemma":[0.990998,0.008529908,0.0003223538,0.00002312671,0.00001541956,0.00001546088,0.00001037314,0.00000601588,0.00007938912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.26449,"threshold_uncertainty_score":0.4769766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07455169416104293,"score_gpt":0.3751062639730025,"score_spread":0.3005545698119595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}