{"id":"W4399363529","doi":"10.1016/j.omtm.2024.101277","title":"Cardiac gene delivery using ultrasound: State of the field","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Methods & Clinical Development","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Canadian Institutes of Health Research; Canadian Cardiovascular Society; Canada Research Chairs; Burroughs Wellcome Fund","keywords":"Gene delivery; Genetic enhancement; Medicine; Visualization; Ultrasound; Bioinformatics; Computational biology; Computer science; Gene; Radiology; Biology; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002623151,0.0006009414,0.0009657297,0.0009329888,0.0004503139,0.002424877,0.0009574695,0.001636983,0.003022511],"category_scores_gemma":[0.001608883,0.0003841622,0.0004671477,0.001232134,0.001509526,0.00199472,0.00099482,0.002095223,0.001352363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000725484,"about_ca_system_score_gemma":0.00168135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009347377,"about_ca_topic_score_gemma":0.0008478295,"domain_scores_codex":[0.9994628,0.0001156701,0.00005839318,0.0001290665,0.0001811357,0.00005302257],"domain_scores_gemma":[0.9974826,0.001674941,0.0002356718,0.00007589386,0.0003663636,0.0001645697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002548708,0.0002579145,0.0007227619,0.01021398,0.00006376834,0.0001387314,0.0003861294,0.0007919582,0.02018635,0.01039028,0.00757969,0.9490137],"study_design_scores_gemma":[0.00003985102,0.001308547,0.002324386,0.004935607,0.0002896373,0.001422098,0.0006339484,0.002070259,0.04461295,0.007644953,0.9345753,0.00014243],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002409906,0.9882472,0.003989113,0.00152345,0.0002179796,0.00002012638,0.00002857956,0.00004515128,0.003518458],"genre_scores_gemma":[0.01359941,0.9807475,0.003014048,0.0008135141,0.0005772545,0.00004054412,0.00007239602,0.00001612354,0.00111923],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003022511,"threshold_uncertainty_score":0.01387274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04017799821711171,"score_gpt":0.3764078030224022,"score_spread":0.3362298048052905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}