{"id":"W4399364945","doi":"10.1016/j.heliyon.2024.e32424","title":"Lack of correlation between in vitro and within patient measures of P. aeruginosa biofilms in cystic fibrosis","year":2024,"lang":"en","type":"article","venue":"Heliyon","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"Canadian Glycomics Network; Cystic Fibrosis Canada; Cystic Fibrosis Foundation","keywords":"Sputum; Biofilm; Pseudomonas aeruginosa; Microbiology; Cystic fibrosis; In vitro; Staining; In vivo; Biology; Ex vivo; Pathology; Medicine; Bacteria; Biochemistry; Tuberculosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001787829,0.0002509824,0.0004668905,0.0004658117,0.0003191802,0.001013655,0.0002800836,0.000727963,0.001186612],"category_scores_gemma":[0.005683783,0.0002596457,0.0002107434,0.0002899764,0.0004191172,0.0004688661,0.0004904657,0.000560653,0.0003017097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002600458,"about_ca_system_score_gemma":0.0002211643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007651661,"about_ca_topic_score_gemma":0.001234639,"domain_scores_codex":[0.9972242,0.001000779,0.0002603428,0.0005751133,0.0008041118,0.0001354359],"domain_scores_gemma":[0.9963373,0.001626268,0.0006894055,0.0005549729,0.0005426927,0.0002494417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008540109,0.0001930968,0.4810275,0.000475291,0.00030961,0.0003398919,0.00178755,0.0009412198,0.4954054,0.0003610658,0.0003561269,0.01794916],"study_design_scores_gemma":[0.00001498958,0.00220088,0.8568634,0.00007039793,0.0002640649,0.002541206,0.001285538,0.004174989,0.1286639,0.0004143301,0.003473695,0.00003258371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890815,0.001975251,0.006657514,0.0001392351,0.00004619446,0.00004251349,0.0004522943,0.00003496377,0.001570403],"genre_scores_gemma":[0.9976653,0.0002245646,0.001360663,0.00004899894,0.00001218507,0.0000379315,0.0003004622,0.000007386933,0.0003426216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001787829,"threshold_uncertainty_score":0.009455025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01984725557229782,"score_gpt":0.2478431206566322,"score_spread":0.2279958650843343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}