{"id":"W4399427988","doi":"10.1016/j.talanta.2024.126379","title":"CRISPR-Hg: Rapid and visual detection of Hg2+ based on PCR coupled with CRISPR/Cas12a","year":2024,"lang":"en","type":"article","venue":"Talanta","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ministry of Education and Child Care","funders":"Agriculture Research System of China; Jilin Province Development and Reform Commission","keywords":"Chemistry; CRISPR; Computational biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001125352,0.001384355,0.001423929,0.001305057,0.0008616093,0.001318594,0.001926033,0.001577772,0.005814246],"category_scores_gemma":[0.000911762,0.001089961,0.0009879919,0.0007462974,0.001173544,0.0006657303,0.001433803,0.002608616,0.005169475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009351202,"about_ca_system_score_gemma":0.001114441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002671677,"about_ca_topic_score_gemma":0.005446312,"domain_scores_codex":[0.9976529,0.0002543512,0.0001449461,0.0007357248,0.0008950687,0.0003169923],"domain_scores_gemma":[0.9992435,0.0002085523,0.0001797985,0.0001196015,0.0001067769,0.0001418823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007105369,0.00002013461,0.00009966578,0.00007906907,0.000009745181,0.00005514633,0.00003341533,0.0000844686,0.9950017,0.0002696273,0.0009626684,0.003313256],"study_design_scores_gemma":[0.00001424297,0.00004018045,0.000508192,0.000008585061,0.00001148665,0.0002318222,0.00001555439,0.001133351,0.9916233,0.0001001791,0.006292515,0.00002059834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1758532,0.001652561,0.7679025,0.001222579,0.000463289,0.0008981932,0.007380818,0.03012592,0.01450101],"genre_scores_gemma":[0.4089776,0.001394256,0.5310973,0.0009614447,0.00005951547,0.001134126,0.01263958,0.004670135,0.03906614],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.005814246,"threshold_uncertainty_score":0.0194506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004990033603576034,"score_gpt":0.2724432883616216,"score_spread":0.2674532547580456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}