{"id":"W4399443861","doi":"10.1002/ped4.12429","title":"Low‐dose immune tolerance induction for severe hemophilia A inhibitor patients: Immunosuppressants are generally not necessary for inhibitor‐titer below 200 BU/mL","year":2024,"lang":"en","type":"article","venue":"Pediatric Investigation","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Beijing Municipal Science and Technology Commission; National Natural Science Foundation of China","keywords":"Regimen; Medicine; Rituximab; Internal medicine; Titer; Prednisone; Gastroenterology; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008429567,0.0001139228,0.000362843,0.0001150253,0.0001167747,0.0003362293,0.0001390343,0.0001324014,0.001251772],"category_scores_gemma":[0.0009922695,0.00004864708,0.0003084983,0.0002252337,0.0001638336,0.0002280483,0.000111525,0.0003361853,0.000170637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001604069,"about_ca_system_score_gemma":0.0002108201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001327171,"about_ca_topic_score_gemma":0.0002482329,"domain_scores_codex":[0.9997333,0.0001242489,0.00003414519,0.00003134121,0.00004151929,0.00003543109],"domain_scores_gemma":[0.9992571,0.0002465367,0.0002741903,0.00004924802,0.00003964306,0.00013319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03531163,0.00319127,0.6920401,0.0004846252,0.0006276979,0.0004990939,0.0001769235,0.0008599063,0.02501787,0.0004569886,0.001873821,0.23946],"study_design_scores_gemma":[0.003001898,0.05868445,0.9179583,0.0001485578,0.0004549716,0.003061388,0.0001587887,0.002127331,0.009479114,0.0003009547,0.004604418,0.00001992739],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977238,0.001190648,0.00017862,0.00005790538,0.00001004581,0.00002281151,0.00004947613,0.000004140701,0.0007625851],"genre_scores_gemma":[0.9994408,0.0001851589,0.00009876988,0.00006428317,0.00001855714,0.00001375835,0.00006984497,0.000001014602,0.0001077336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001251772,"threshold_uncertainty_score":0.00445807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02431701384654268,"score_gpt":0.2762433265242134,"score_spread":0.2519263126776707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}