{"id":"W4399443861","doi":"10.1002/ped4.12429","title":"Low‐dose immune tolerance induction for severe hemophilia A inhibitor patients: Immunosuppressants are generally not necessary for inhibitor‐titer below 200 BU/mL","year":2024,"lang":"en","type":"article","venue":"Pediatric Investigation","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Beijing Municipal Science and Technology Commission; National Natural Science Foundation of China","keywords":"Regimen; Medicine; Rituximab; Internal medicine; Titer; Prednisone; Gastroenterology; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004147173,0.0003866861,0.000454047,0.0004783642,0.0003255044,0.000146058,0.0001443705,0.0003716003,0.0000365433],"category_scores_gemma":[0.0003783976,0.0003308278,0.0002749413,0.0006998943,0.000105754,0.0006786537,0.00006765826,0.0003756444,0.00007473222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000317544,"about_ca_system_score_gemma":0.000464344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002564623,"about_ca_topic_score_gemma":0.000003010245,"domain_scores_codex":[0.9972593,0.00007103581,0.0007202886,0.0007252345,0.0006356849,0.0005884772],"domain_scores_gemma":[0.9983379,0.0001951685,0.0001911281,0.0003787769,0.0006417066,0.0002553011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.007571115,0.003506782,0.3562218,0.02691113,0.0011166,0.000168224,0.006681276,0.0008433732,0.1798121,0.0003922813,0.3157761,0.1009992],"study_design_scores_gemma":[0.04307044,0.006715559,0.4620293,0.004342884,0.003103736,0.0001295901,0.0004705016,0.03408922,0.407804,0.007229518,0.02735311,0.003662118],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987089,0.002604655,0.0001393043,0.004011123,0.00228857,0.003224925,0.0003306813,0.0002687667,0.00004297671],"genre_scores_gemma":[0.9842801,0.0005399834,0.002294599,0.0004276531,0.006657124,0.001042009,0.001880419,0.0001387326,0.002739355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.288423,"threshold_uncertainty_score":0.9999143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02431701384654268,"score_gpt":0.2762433265242134,"score_spread":0.2519263126776707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}