{"id":"W4399444585","doi":"10.1007/s10067-024-06991-8","title":"Durable control of psoriatic arthritis with guselkumab across domains and patient characteristics: post hoc analysis of a phase 3 study","year":2024,"lang":"en","type":"article","venue":"Clinical Rheumatology","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Janssen Research and Development; Janssen Scientific Affairs","keywords":"Medicine; Dactylitis; Psoriatic arthritis; Internal medicine; Enthesitis; Rheumatology; Ustekinumab; Physical therapy; Clinical endpoint; Randomized controlled trial; Post-hoc analysis; Disease; Adalimumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00947366,0.001668051,0.003468687,0.0004146798,0.0005569503,0.001334004,0.0007632922,0.0008171432,0.003529441],"category_scores_gemma":[0.003504493,0.0005418822,0.004037865,0.0006383571,0.00108489,0.001040284,0.000670507,0.002436875,0.0005533735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009255075,"about_ca_system_score_gemma":0.002507531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007039523,"about_ca_topic_score_gemma":0.001870235,"domain_scores_codex":[0.9963322,0.002320089,0.0001621795,0.0003916324,0.0002653826,0.0005286458],"domain_scores_gemma":[0.9961948,0.001088624,0.0009926928,0.00088924,0.0002471733,0.000587487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.953272,0.0120335,0.007175438,0.0002022296,0.004117928,0.00004880263,0.0000971661,0.001116255,0.007625316,0.00007273874,0.0007959243,0.0134427],"study_design_scores_gemma":[0.3436168,0.5669464,0.07539994,0.00002620534,0.004731733,0.000131703,0.0001117268,0.002156776,0.004854353,0.0002765692,0.001686591,0.00006128105],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996034,0.0004549827,0.0006579587,0.00006777226,0.00006094674,0.001227741,0.000858781,0.00005280329,0.000585123],"genre_scores_gemma":[0.993732,0.0002074396,0.001209489,0.0001878941,0.0001125947,0.002135874,0.00127041,0.0000379866,0.00110631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00947366,"threshold_uncertainty_score":0.05010211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0155307807033462,"score_gpt":0.355144194021493,"score_spread":0.3396134133181468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}