{"id":"W4399447105","doi":"10.1016/j.mucimm.2024.06.001","title":"Lung influenza virus-specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells","year":2024,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"H2020 European Research Council; National Institutes of Health; University of Glasgow; Rosetrees Trust; Wellcome Trust","keywords":"Lung; Immunology; Cytokine; Antigen; Virology; Virus; Biology; Influenza A virus; Immunological memory; T cell; Medicine; Immunity; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003031622,0.0002962206,0.0003647323,0.000564859,0.0003246614,0.0001081759,0.0001176104,0.0001241743,0.0001071263],"category_scores_gemma":[0.0001208482,0.0002439419,0.00005856991,0.0004837451,0.0002952767,0.0003274957,0.000202732,0.0008950226,0.0002021902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003436649,"about_ca_system_score_gemma":0.0001182594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001178996,"about_ca_topic_score_gemma":0.00004794362,"domain_scores_codex":[0.9979188,0.0001352889,0.000379179,0.0006889211,0.0003594367,0.0005183661],"domain_scores_gemma":[0.9988475,0.0001559285,0.0001164797,0.000458257,0.0003418624,0.00007993713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001969831,0.0004028594,0.006054232,0.0008361011,0.0007973459,0.0004207673,0.002437301,0.001271325,0.9759849,0.0001732604,0.005220168,0.004431947],"study_design_scores_gemma":[0.002203269,0.0007372527,0.06719935,0.0009963058,0.0002343763,0.0004611871,0.002776481,0.004029182,0.8805109,0.00001434857,0.04029138,0.0005459246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800784,0.01499557,0.0005587721,0.0008311183,0.0009751094,0.0008903393,0.00001900197,0.0002468574,0.001404837],"genre_scores_gemma":[0.9955039,0.001938932,0.000446045,0.0001755796,0.000430407,0.0001263736,0.00002724261,0.0000647386,0.001286752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09547392,"threshold_uncertainty_score":0.9947662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03856946322929861,"score_gpt":0.3353110164380345,"score_spread":0.2967415532087359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}