{"id":"W4399452667","doi":"10.1200/jco.2024.42.17_suppl.lba8500","title":"Sacituzumab govitecan (SG) vs docetaxel (doc) in patients (pts) with metastatic non-small cell lung cancer (mNSCLC) previously treated with platinum (PT)-based chemotherapy (chemo) and PD(L)-1inhibitors (IO): Primary results from the phase 3 EVOKE-01 study.","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Docetaxel; Internal medicine; Clinical endpoint; Lung cancer; Adverse effect; Neutropenia; Chemotherapy; Phases of clinical research; Toxicity; Progression-free survival; Oncology; Gastroenterology; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001047075,0.0007039494,0.00139044,0.0003542945,0.0001979732,0.0007895183,0.0005631069,0.001021257,0.002507829],"category_scores_gemma":[0.001082272,0.0003297262,0.001130112,0.000414155,0.0007060597,0.0007041758,0.0003220967,0.001938603,0.0004796674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007231496,"about_ca_system_score_gemma":0.0008694056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001194667,"about_ca_topic_score_gemma":0.00464831,"domain_scores_codex":[0.9996662,0.0001780517,0.00002343552,0.00003987082,0.00002694123,0.00006545075],"domain_scores_gemma":[0.9993551,0.0001740056,0.0001638468,0.00003074669,0.00002077057,0.0002555966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9317945,0.008522555,0.004610388,0.0004378945,0.0008886356,0.00007792564,0.0001099821,0.001349467,0.0044733,0.0001441326,0.001516743,0.0460746],"study_design_scores_gemma":[0.5890935,0.3817055,0.02122659,0.00007985314,0.001434593,0.0002074843,0.0001100048,0.001622051,0.001771508,0.0003118129,0.00240618,0.00003095913],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954478,0.002237347,0.00009330911,0.0002525182,0.0001102957,0.0004079061,0.0003936144,0.00003419314,0.001023041],"genre_scores_gemma":[0.9968213,0.00104752,0.0001708815,0.0003334603,0.00009703702,0.0002536699,0.0005409014,0.000006753476,0.0007284144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002507829,"threshold_uncertainty_score":0.008389533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03269214412664184,"score_gpt":0.4093971086055671,"score_spread":0.3767049644789252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}