{"id":"W4399458977","doi":"10.1080/03007995.2024.2366443","title":"Update on efficacy of the approved remdesivir regimen for treatment of COVID-19: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials","year":2024,"lang":"en","type":"review","venue":"Current Medical Research and Opinion","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; George & Fay Yee Centre for Healthcare Innovation","funders":"","keywords":"Medicine; Meta-analysis; Regimen; Randomized controlled trial; Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Intensive care medicine; Internal medicine; Virology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03388984,0.002924192,0.02002578,0.01139445,0.0005941027,0.004181005,0.002748074,0.002366213,0.004221575],"category_scores_gemma":[0.08261242,0.001844239,0.03288755,0.007753152,0.000948381,0.003349897,0.001919053,0.002549388,0.0004389849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00451796,"about_ca_system_score_gemma":0.008177976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006613764,"about_ca_topic_score_gemma":0.01556818,"domain_scores_codex":[0.9785699,0.009587404,0.007287241,0.001486517,0.002666357,0.0004025707],"domain_scores_gemma":[0.935889,0.04678364,0.00993373,0.00157378,0.00534718,0.000472656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001035211,0.00002571267,0.00118865,0.7485273,0.2102601,0.00007707656,0.00009492422,0.0003775187,0.000188648,0.0003717552,0.001794983,0.03605817],"study_design_scores_gemma":[0.001113127,0.0002695317,0.002678878,0.1855856,0.7989191,0.0001546464,0.00006041516,0.0003427877,0.0001859467,0.0009461939,0.009691012,0.00005272958],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009097485,0.9965698,0.0006439337,0.0004806283,0.0002505648,0.0004115588,0.0004977343,0.00002618316,0.0002099508],"genre_scores_gemma":[0.0411129,0.949323,0.004440561,0.002026471,0.0004988576,0.00142704,0.0008660561,0.00004673174,0.0002583812],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03388984,"threshold_uncertainty_score":0.1792288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5002402108300233,"score_gpt":0.6203149645727072,"score_spread":0.1200747537426838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}