{"id":"W4399481734","doi":"10.1136/annrheumdis-2024-eular.4696","title":"POS0053 CARDIOVASCULAR SAFETY OF COLCHICINE AND NSAID PROPHYLAXIS WITH URATE-LOWERING THERAPY INITIATION: TARGET TRIAL EMULATION (TTE) ANALYSES","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Gout, Hyperuricemia, Uric Acid","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Research Canada","funders":"","keywords":"Colchicine; Emulation; Medicine; Pharmacology; Internal medicine; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003573046,0.001514848,0.002227215,0.0003588407,0.0003909462,0.001764685,0.0006132746,0.001769998,0.0118086],"category_scores_gemma":[0.004802324,0.0006069509,0.005620015,0.0005616187,0.000818231,0.001596724,0.0006653678,0.004196611,0.001497877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006828356,"about_ca_system_score_gemma":0.0008857328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007804043,"about_ca_topic_score_gemma":0.002122216,"domain_scores_codex":[0.9980066,0.001245728,0.0001291861,0.0002365395,0.0001166639,0.0002651693],"domain_scores_gemma":[0.9978608,0.001058856,0.000362461,0.0002441698,0.0001412263,0.0003324753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9626185,0.001352606,0.005919337,0.0007584638,0.01050512,0.0000903847,0.00004549212,0.0006794865,0.001524599,0.0004839396,0.002146642,0.01387554],"study_design_scores_gemma":[0.7431265,0.1517943,0.06124786,0.0002672913,0.02721102,0.0002143003,0.0002166778,0.003740602,0.00178971,0.003027676,0.007231107,0.0001329743],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9679199,0.007936805,0.002079455,0.00141457,0.001113847,0.0009691543,0.004947568,0.0002619317,0.01335675],"genre_scores_gemma":[0.9893255,0.001259097,0.0006014558,0.001309733,0.0005094843,0.0004843115,0.002264808,0.00004029232,0.00420529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0118086,"threshold_uncertainty_score":0.03950369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06995949767068035,"score_gpt":0.3379173329422202,"score_spread":0.2679578352715398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}