{"id":"W4399482038","doi":"10.1136/annrheumdis-2024-eular.2314","title":"POS0798 EFFICACY, SAFETY AND RADIOGRAPHIC OUTCOMES FROM THE PHASE 3 SELECT-AXIS 2 STUDY OF UPADACITINIB IN PATIENTS WITH ACTIVE ANKYLOSING SPONDYLITIS AND AN INADEQUATE RESPONSE TO BIOLOGIC DMARD THERAPY: 2-YEAR DATA","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; Arthritis Society; University of Toronto; University Health Network","funders":"","keywords":"Ankylosing spondylitis; Medicine; Radiography; Internal medicine; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006135396,0.001415386,0.003035527,0.0007054395,0.0005857191,0.001821743,0.0008791659,0.00184533,0.003355788],"category_scores_gemma":[0.003232738,0.00056149,0.005457392,0.001095065,0.0009024845,0.002355688,0.0006333375,0.003274255,0.001097078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007048929,"about_ca_system_score_gemma":0.001135117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008080135,"about_ca_topic_score_gemma":0.002769656,"domain_scores_codex":[0.9977598,0.0009761623,0.0002619929,0.0002608528,0.0004479203,0.000293146],"domain_scores_gemma":[0.9959925,0.001263037,0.001347141,0.0003493955,0.0004382721,0.0006097126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7246326,0.005552359,0.09770095,0.003706286,0.03104785,0.0005528856,0.0002844463,0.005433835,0.006928029,0.0005809565,0.01827627,0.1053035],"study_design_scores_gemma":[0.3498775,0.1680627,0.4201181,0.0008324265,0.0310979,0.001810631,0.0004216336,0.002837642,0.003338944,0.001198113,0.0200765,0.0003277521],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9389774,0.02889983,0.0008645196,0.001513138,0.000319372,0.0007052713,0.02196747,0.0001324286,0.006620604],"genre_scores_gemma":[0.9591243,0.007471897,0.000616221,0.002105512,0.000345142,0.0006259989,0.02763372,0.00004743519,0.002029749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006135396,"threshold_uncertainty_score":0.0324474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05781690662898581,"score_gpt":0.3535003894930224,"score_spread":0.2956834828640366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}