{"id":"W4399482262","doi":"10.1136/annrheumdis-2024-eular.1845","title":"POS0874 COMPARABLE SAFETY AND EFFECTIVENESS AMONG NEW USERS OF BIOSIMILAR VS ORIGINATOR ANTI-TNFS IN INFLAMMATORY ARTHRITIS: POPULATION-BASED EVIDENCE FROM A POLICY CHANGE","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University; Research Canada; University of British Columbia","funders":"","keywords":"Biosimilar; Medicine; Population; Arthritis; Computer science; Pharmacology; Internal medicine; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01502388,0.0004950693,0.001870485,0.0007625253,0.0004748566,0.002320433,0.0008141095,0.003475901,0.008432188],"category_scores_gemma":[0.03217955,0.0004476485,0.004639509,0.001533401,0.002089659,0.002626989,0.0007062451,0.004463063,0.0008201173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00147878,"about_ca_system_score_gemma":0.001452917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001044282,"about_ca_topic_score_gemma":0.0009886679,"domain_scores_codex":[0.9827057,0.0114359,0.001386274,0.001829684,0.001893661,0.0007486271],"domain_scores_gemma":[0.9550409,0.0304546,0.008815608,0.002271027,0.00193749,0.001480432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7270657,0.002682779,0.05847264,0.004693895,0.02257847,0.0003264256,0.0003870174,0.001286342,0.002389042,0.002699403,0.007582171,0.1698361],"study_design_scores_gemma":[0.3102546,0.1908156,0.386292,0.004939644,0.05503052,0.001333025,0.001174419,0.002506193,0.004662777,0.009670112,0.03298036,0.0003407957],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9144914,0.05683146,0.001548108,0.008443792,0.001911364,0.0003691985,0.004211314,0.0001090883,0.01208416],"genre_scores_gemma":[0.9884576,0.005064692,0.0003721071,0.003557982,0.0008137559,0.0001034564,0.0009820652,0.00002464081,0.000623739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01502388,"threshold_uncertainty_score":0.07945484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04622181934063255,"score_gpt":0.3329080716615825,"score_spread":0.2866862523209499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}