{"id":"W4399482631","doi":"10.1136/annrheumdis-2024-eular.4903","title":"POS0058 IMPACT OF BIMEKIZUMAB ON MRI INFLAMMATORY AND STRUCTURAL LESIONS IN THE SACROILIAC JOINTS OF PATIENTS WITH AXIAL SPONDYLOARTHRITIS: 52-WEEK RESULTS AND POST HOC ANALYSES FROM THE BE MOBILE 1 AND 2 PHASE 3 STUDIES","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Axial spondyloarthritis; Medicine; Sacroiliac joint; Magnetic resonance imaging; Post-hoc analysis; Physical medicine and rehabilitation; Physical therapy; Radiology; Internal medicine; Sacroiliitis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003089185,0.001176494,0.00285415,0.0003611722,0.0003480865,0.001275519,0.0006223634,0.00132172,0.005063795],"category_scores_gemma":[0.002629757,0.0005536231,0.00391353,0.0003396512,0.0005912771,0.001376835,0.0005086944,0.002236825,0.0009356309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004813727,"about_ca_system_score_gemma":0.0008258487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007584416,"about_ca_topic_score_gemma":0.001774454,"domain_scores_codex":[0.9983742,0.0009357454,0.0001106795,0.0001956646,0.0001247567,0.0002589573],"domain_scores_gemma":[0.9981968,0.0008772183,0.0003714881,0.0001591449,0.0001328473,0.0002626153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9605163,0.003390866,0.006309756,0.0003901616,0.003869946,0.00006253244,0.00005373895,0.0007231839,0.004409345,0.00005945444,0.0007683649,0.01944621],"study_design_scores_gemma":[0.4193232,0.4477843,0.1166877,0.0001209417,0.007507157,0.0001804627,0.0002324805,0.001612918,0.003777452,0.000268015,0.002415117,0.00009026738],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994278,0.00229067,0.0002319008,0.0002119219,0.0001732043,0.0002808071,0.001069241,0.00003567414,0.001428556],"genre_scores_gemma":[0.9957035,0.0004912778,0.0003325795,0.0002767238,0.0001399223,0.0002652147,0.001232123,0.0000160426,0.001542616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005063795,"threshold_uncertainty_score":0.01694012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04804476592149347,"score_gpt":0.3718958077875296,"score_spread":0.3238510418660361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}