{"id":"W4399482868","doi":"10.1136/annrheumdis-2024-eular.1846","title":"AB0192 COMPARABLE SAFETY AND EFFECTIVENESS AFTER TRANSITION TO A BIOSIMILAR ANTI-TNF IN INFLAMMATORY ARTHRITIS: POPULATION-BASED EVIDENCE FROM A POLICY CHANGE","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University; Research Canada; University of British Columbia","funders":"","keywords":"Biosimilar; Inflammatory arthritis; Arthritis; Transition (genetics); Medicine; Tumor necrosis factor alpha; Population; Immunology; Internal medicine; Chemistry; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01702276,0.0005668017,0.001944458,0.0007863839,0.0005511934,0.002904766,0.00105539,0.003886712,0.007615742],"category_scores_gemma":[0.04139666,0.0003872752,0.005609582,0.001404513,0.002065663,0.002589671,0.0009605775,0.005529071,0.0006237185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002637153,"about_ca_system_score_gemma":0.002648591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003759574,"about_ca_topic_score_gemma":0.002255213,"domain_scores_codex":[0.9773704,0.01389988,0.002083592,0.002531778,0.002684177,0.001430151],"domain_scores_gemma":[0.9537482,0.03005471,0.009903602,0.002098738,0.002385198,0.001809563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7011575,0.005173394,0.05113479,0.006407728,0.02935951,0.0004285983,0.0006392758,0.001733,0.002392614,0.003195282,0.006830488,0.1915478],"study_design_scores_gemma":[0.3016087,0.1653038,0.3727847,0.007783216,0.08662238,0.001112652,0.001719541,0.002818925,0.005950076,0.01238906,0.04157487,0.0003319331],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.89176,0.07449409,0.001636609,0.0158406,0.002752253,0.0005187231,0.00318973,0.0000987186,0.009709344],"genre_scores_gemma":[0.9859757,0.006199758,0.0004718356,0.004745794,0.001004529,0.00013289,0.0008492927,0.00002025081,0.0005999967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01702276,"threshold_uncertainty_score":0.09002602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04027514274412541,"score_gpt":0.3288282581124399,"score_spread":0.2885531153683145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}