{"id":"W4399483106","doi":"10.1136/annrheumdis-2024-eular.2132","title":"AB1410 EARLY SYMPTOMATIC IMPROVEMENT WITH GUSELKUMAB INDUCTION TREATMENT IN MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS: RESULTS FROM THE PHASE 3 QUASAR INDUCTION STUDY","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Eosinophilic Esophagitis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Ulcerative colitis; Medicine; Quasar; Phase (matter); Internal medicine; Gastroenterology; Physics; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001822711,0.001292667,0.002917959,0.0004333213,0.0004193152,0.0009770804,0.0008278452,0.001114113,0.002253624],"category_scores_gemma":[0.0006862859,0.0003583278,0.001890606,0.000422087,0.001113241,0.0008876214,0.0003147328,0.003072269,0.0006686078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006035546,"about_ca_system_score_gemma":0.0008993856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008345366,"about_ca_topic_score_gemma":0.001628395,"domain_scores_codex":[0.9993837,0.0003013347,0.00003022144,0.00006224463,0.00006101144,0.0001614275],"domain_scores_gemma":[0.9992163,0.0001827474,0.0001377316,0.00008092099,0.0000428645,0.0003394285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7268986,0.06330334,0.00680919,0.000860711,0.001853237,0.0003832661,0.0002628036,0.001446932,0.05145698,0.0002011802,0.001966875,0.1445569],"study_design_scores_gemma":[0.3039957,0.6585345,0.03053338,0.00004693138,0.0007411169,0.0002541464,0.00007993093,0.0005850753,0.003699005,0.0001052593,0.001382295,0.00004265251],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953063,0.002577576,0.0002705489,0.0002406158,0.00008413543,0.0003138637,0.0003992928,0.00005729648,0.0007503506],"genre_scores_gemma":[0.9946283,0.001836963,0.0005685271,0.0005249804,0.0001652501,0.0002731058,0.0009139367,0.0000257449,0.001063154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002917959,"threshold_uncertainty_score":0.009639502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05356721853829596,"score_gpt":0.343808716522655,"score_spread":0.2902414979843591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}