{"id":"W4399483149","doi":"10.1136/annrheumdis-2024-eular.lba25","title":"LBA0001 EFFICACY AND SAFETY OF UPADACITINIB IN PATIENTS WITH GIANT CELL ARTERITIS (SELECT-GCA): A DOUBLE-BLIND, RANDOMIZED CONTROLLED PHASE 3 TRIAL","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Vasculitis and related conditions","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Giant cell arteritis; Double blind; Medicine; Randomized controlled trial; Internal medicine; Vasculitis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00138525,0.001975954,0.003713988,0.0004474052,0.0005490792,0.001509972,0.0009309199,0.002265851,0.007604796],"category_scores_gemma":[0.001608939,0.0008173754,0.002426646,0.0004891416,0.001570444,0.001482029,0.0004045769,0.004173959,0.001395567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006317291,"about_ca_system_score_gemma":0.001066228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009109605,"about_ca_topic_score_gemma":0.002016902,"domain_scores_codex":[0.999496,0.0002308627,0.00003480081,0.00008912678,0.00004358735,0.0001055934],"domain_scores_gemma":[0.999198,0.0002451335,0.0001844906,0.00006366327,0.00005745171,0.0002513196],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9783831,0.003700566,0.000466367,0.0008542101,0.001198652,0.00004011593,0.00004209381,0.0002470824,0.001607509,0.0001147049,0.0009227175,0.01242281],"study_design_scores_gemma":[0.9705936,0.02720496,0.0008827978,0.00003324799,0.0004330803,0.00002978069,0.00001741367,0.000229973,0.0001630647,0.00008379024,0.0003142852,0.000013893],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820613,0.00849709,0.0007702859,0.0007727176,0.0006826224,0.002877255,0.001260191,0.0002245884,0.002853877],"genre_scores_gemma":[0.986819,0.003740955,0.001183053,0.001250208,0.0004853393,0.002861582,0.00121528,0.00003326665,0.002411313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007604796,"threshold_uncertainty_score":0.02544063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0186405305728598,"score_gpt":0.2994161056757746,"score_spread":0.2807755751029148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}